node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70667.1 | ABK72117.1 | MSMEG_1873 | MSMEG_1033 | Thymidylate kinase; Identified by match to protein family HMM PF02223. | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.918 |
ABK70667.1 | cmk | MSMEG_1873 | MSMEG_3739 | Thymidylate kinase; Identified by match to protein family HMM PF02223. | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.407 |
ABK70667.1 | gmk | MSMEG_1873 | MSMEG_3051 | Thymidylate kinase; Identified by match to protein family HMM PF02223. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.454 |
ABK70667.1 | ndk | MSMEG_1873 | MSMEG_4627 | Thymidylate kinase; Identified by match to protein family HMM PF02223. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.929 |
ABK70667.1 | nrdB | MSMEG_1873 | MSMEG_0358 | Thymidylate kinase; Identified by match to protein family HMM PF02223. | Ribonucleoside-diphosphate reductase, beta subunit; Probable oxidase that might be involved in lipid metabolism. Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily. | 0.918 |
ABK70667.1 | nrdE1 | MSMEG_1873 | MSMEG_1019 | Thymidylate kinase; Identified by match to protein family HMM PF02223. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity); Belongs to the ribonucleoside diphosphate reductase large chain family. | 0.941 |
ABK72117.1 | ABK70667.1 | MSMEG_1033 | MSMEG_1873 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Thymidylate kinase; Identified by match to protein family HMM PF02223. | 0.918 |
ABK72117.1 | adk | MSMEG_1033 | MSMEG_1484 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.915 |
ABK72117.1 | cmk | MSMEG_1033 | MSMEG_3739 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.914 |
ABK72117.1 | gmk | MSMEG_1033 | MSMEG_3051 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.907 |
ABK72117.1 | ndk | MSMEG_1033 | MSMEG_4627 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.910 |
ABK72117.1 | nrdB | MSMEG_1033 | MSMEG_0358 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase, beta subunit; Probable oxidase that might be involved in lipid metabolism. Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily. | 0.925 |
ABK72117.1 | nrdE1 | MSMEG_1033 | MSMEG_1019 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity); Belongs to the ribonucleoside diphosphate reductase large chain family. | 0.997 |
ABK72117.1 | pyk | MSMEG_1033 | MSMEG_0154 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.908 |
ABK72117.1 | pyk-2 | MSMEG_1033 | MSMEG_3227 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.908 |
ABK72117.1 | relA | MSMEG_1033 | MSMEG_2965 | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.904 |
adk | ABK72117.1 | MSMEG_1484 | MSMEG_1033 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.915 |
adk | cmk | MSMEG_1484 | MSMEG_3739 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.524 |
adk | gmk | MSMEG_1484 | MSMEG_3051 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.925 |
adk | ndk | MSMEG_1484 | MSMEG_4627 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.945 |