node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70588.1 | ABK71183.1 | MSMEG_3467 | MSMEG_2983 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.814 |
ABK70588.1 | ABK71747.1 | MSMEG_3467 | MSMEG_2201 | Conserved hypothetical protein. | ZbpA protein; Identified by match to protein family HMM PF01575. | 0.814 |
ABK70588.1 | ABK74785.1 | MSMEG_3467 | MSMEG_6630 | Conserved hypothetical protein. | Identified by match to protein family HMM PF00903. | 0.843 |
ABK70588.1 | mspB | MSMEG_3467 | MSMEG_0520 | Conserved hypothetical protein. | Porin; A backup porin induced when MspA, the major porin, is deleted. Probably forms a water-filled channel which favors the permeation of cations. There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion. A triple mspA- mspC-mspD deletion mutant has low but detectable channel activity. Different conductance values with maxima at 2.3 and 4.6 nanosiemens might be caused by a simultaneous reconstitution of MspB channels into the membrane or by the existence of different MspB conformations. Belongs to the mycobacterial porin (TC 1.B.24) family. | 0.591 |
ABK71059.1 | mspB | MSMEG_0519 | MSMEG_0520 | Conserved hypothetical protein. | Porin; A backup porin induced when MspA, the major porin, is deleted. Probably forms a water-filled channel which favors the permeation of cations. There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion. A triple mspA- mspC-mspD deletion mutant has low but detectable channel activity. Different conductance values with maxima at 2.3 and 4.6 nanosiemens might be caused by a simultaneous reconstitution of MspB channels into the membrane or by the existence of different MspB conformations. Belongs to the mycobacterial porin (TC 1.B.24) family. | 0.472 |
ABK71183.1 | ABK70588.1 | MSMEG_2983 | MSMEG_3467 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.814 |
ABK71183.1 | ABK71747.1 | MSMEG_2983 | MSMEG_2201 | Conserved hypothetical protein. | ZbpA protein; Identified by match to protein family HMM PF01575. | 0.815 |
ABK71183.1 | ABK74785.1 | MSMEG_2983 | MSMEG_6630 | Conserved hypothetical protein. | Identified by match to protein family HMM PF00903. | 0.814 |
ABK71183.1 | mspB | MSMEG_2983 | MSMEG_0520 | Conserved hypothetical protein. | Porin; A backup porin induced when MspA, the major porin, is deleted. Probably forms a water-filled channel which favors the permeation of cations. There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion. A triple mspA- mspC-mspD deletion mutant has low but detectable channel activity. Different conductance values with maxima at 2.3 and 4.6 nanosiemens might be caused by a simultaneous reconstitution of MspB channels into the membrane or by the existence of different MspB conformations. Belongs to the mycobacterial porin (TC 1.B.24) family. | 0.591 |
ABK71747.1 | ABK70588.1 | MSMEG_2201 | MSMEG_3467 | ZbpA protein; Identified by match to protein family HMM PF01575. | Conserved hypothetical protein. | 0.814 |
ABK71747.1 | ABK71183.1 | MSMEG_2201 | MSMEG_2983 | ZbpA protein; Identified by match to protein family HMM PF01575. | Conserved hypothetical protein. | 0.815 |
ABK71747.1 | ABK74785.1 | MSMEG_2201 | MSMEG_6630 | ZbpA protein; Identified by match to protein family HMM PF01575. | Identified by match to protein family HMM PF00903. | 0.823 |
ABK71747.1 | mspB | MSMEG_2201 | MSMEG_0520 | ZbpA protein; Identified by match to protein family HMM PF01575. | Porin; A backup porin induced when MspA, the major porin, is deleted. Probably forms a water-filled channel which favors the permeation of cations. There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion. A triple mspA- mspC-mspD deletion mutant has low but detectable channel activity. Different conductance values with maxima at 2.3 and 4.6 nanosiemens might be caused by a simultaneous reconstitution of MspB channels into the membrane or by the existence of different MspB conformations. Belongs to the mycobacterial porin (TC 1.B.24) family. | 0.593 |
ABK74785.1 | ABK70588.1 | MSMEG_6630 | MSMEG_3467 | Identified by match to protein family HMM PF00903. | Conserved hypothetical protein. | 0.843 |
ABK74785.1 | ABK71183.1 | MSMEG_6630 | MSMEG_2983 | Identified by match to protein family HMM PF00903. | Conserved hypothetical protein. | 0.814 |
ABK74785.1 | ABK71747.1 | MSMEG_6630 | MSMEG_2201 | Identified by match to protein family HMM PF00903. | ZbpA protein; Identified by match to protein family HMM PF01575. | 0.823 |
ABK74785.1 | mspB | MSMEG_6630 | MSMEG_0520 | Identified by match to protein family HMM PF00903. | Porin; A backup porin induced when MspA, the major porin, is deleted. Probably forms a water-filled channel which favors the permeation of cations. There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion. A triple mspA- mspC-mspD deletion mutant has low but detectable channel activity. Different conductance values with maxima at 2.3 and 4.6 nanosiemens might be caused by a simultaneous reconstitution of MspB channels into the membrane or by the existence of different MspB conformations. Belongs to the mycobacterial porin (TC 1.B.24) family. | 0.591 |
mscL | mspA | MSMEG_5482 | MSMEG_0965 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Porin; The major porin in this organism, forms a water-filled channel which favors the permeation of cations, amino acids, iron Fe(3+) and less efficiently phosphate. Does not transport Fe-ExoMS, the predominant siderophore. Plays a role in transport of beta-lactamase and hydrophilic fluoroquinolone antibiotics such as norfloxacin as well as chloramphenicol. There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion. Different conductance values with maxima at 2.3 and 4.6 nanosiemens might be caused by a simultaneous reconstitution of MspA [...] | 0.406 |
mscL | mspB | MSMEG_5482 | MSMEG_0520 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Porin; A backup porin induced when MspA, the major porin, is deleted. Probably forms a water-filled channel which favors the permeation of cations. There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion. A triple mspA- mspC-mspD deletion mutant has low but detectable channel activity. Different conductance values with maxima at 2.3 and 4.6 nanosiemens might be caused by a simultaneous reconstitution of MspB channels into the membrane or by the existence of different MspB conformations. Belongs to the mycobacterial porin (TC 1.B.24) family. | 0.478 |
mspA | mscL | MSMEG_0965 | MSMEG_5482 | Porin; The major porin in this organism, forms a water-filled channel which favors the permeation of cations, amino acids, iron Fe(3+) and less efficiently phosphate. Does not transport Fe-ExoMS, the predominant siderophore. Plays a role in transport of beta-lactamase and hydrophilic fluoroquinolone antibiotics such as norfloxacin as well as chloramphenicol. There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion. Different conductance values with maxima at 2.3 and 4.6 nanosiemens might be caused by a simultaneous reconstitution of MspA [...] | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.406 |