STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (389 aa)    
Predicted Functional Partners:
ddl
D-alanine--D-alanine ligase; Cell wall formation.
 
 
 0.998
ABK76013.1
Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150.
  
 0.993
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
 0.985
ald
Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. May be required for the adaptation from aerobic growth to anaerobic dormancy. I could be involved in the maintenance of the NAD pool during the shift to an anaerobic dormant state in which oxygen as a terminal electron acceptor becomes limited.
  
 
 0.964
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
  
 0.936
rimI
Ribosomal-protein-alanine acetyltransferase; Identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575.
 
  
 0.910
ABK70019.1
Peptidase M22, glycoprotease; Identified by match to protein family HMM PF00814.
 
  
 0.900
ABK73567.1
Aspartate aminotransferase; Identified by match to protein family HMM PF00155.
  
 
 0.874
ABK75088.1
Alpha/beta hydrolase fold; Identified by match to protein family HMM PF00561.
  
  
 0.870
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
  
 0.870
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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