STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtrADNA-binding response regulator MtrA; Member of the two-component regulatory system MtrA/MtrB, responding to environmental signals (Probable). Controls expression of a number of genes including dnaA, ripA, fbpB and probably itself. Probably plays a role in cell division. (228 aa)    
Predicted Functional Partners:
mtrB
Sensor histidine kinase MtrB; Member of the two-component regulatory system MtrA/MtrB. Probably functions as a membrane-associated protein kinase that phosphorylates MtrA in response to environmental signals (By similarity). MtrB may be active only at septa where it promotes MtrA phosphorylation and MtrA regulon expression, probably playing a role in cell division.
 
 0.999
senX3
Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system.
 
 0.963
lpqB
LpqB protein; May modulate activity of the MtrAB system in controlling homeostasis of the cell wall and cell division. Belongs to the LpqB lipoprotein family.
  
  
 0.939
ABK71265.1
Sensor-type histidine kinase PrrB; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
 0.938
ABK70626.1
Sensor histidine kinase PhoR; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 0.896
ABK72171.1
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 0.892
ABK71475.1
Histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 
 0.888
ABK74047.1
Sensor-type histidine kinase PrrB; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
 0.885
ABK72371.1
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
 0.867
ABK75033.1
Sensor-type histidine kinase PrrB; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 
 0.839
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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