node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69728.1 | ABK76183.1 | MSMEG_2416 | MSMEG_2413 | Conserved hypothetical protein. | Putative methyltransferase; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095. | 0.536 |
ABK69728.1 | coaD | MSMEG_2416 | MSMEG_2414 | Conserved hypothetical protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.884 |
ABK76183.1 | ABK69728.1 | MSMEG_2413 | MSMEG_2416 | Putative methyltransferase; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095. | Conserved hypothetical protein. | 0.536 |
ABK76183.1 | coaD | MSMEG_2413 | MSMEG_2414 | Putative methyltransferase; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.990 |
ABK76183.1 | pyrH | MSMEG_2413 | MSMEG_2540 | Putative methyltransferase; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.448 |
coaA | coaBC | MSMEG_5252 | MSMEG_3054 | Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.982 |
coaA | coaD | MSMEG_5252 | MSMEG_2414 | Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.990 |
coaA | coaX | MSMEG_5252 | MSMEG_6096 | Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554. | Bvg accessory factor family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.979 |
coaA | panC | MSMEG_5252 | MSMEG_6097 | Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.945 |
coaBC | coaA | MSMEG_3054 | MSMEG_5252 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554. | 0.982 |
coaBC | coaD | MSMEG_3054 | MSMEG_2414 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.994 |
coaBC | coaX | MSMEG_3054 | MSMEG_6096 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Bvg accessory factor family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.972 |
coaBC | guaA | MSMEG_3054 | MSMEG_1610 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.463 |
coaBC | panC | MSMEG_3054 | MSMEG_6097 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.955 |
coaBC | panE-2 | MSMEG_3054 | MSMEG_6374 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.852 |
coaBC | ribF | MSMEG_3054 | MSMEG_2653 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; match to protein family HMM TIGR00125; Belongs to the ribF family. | 0.605 |
coaD | ABK69728.1 | MSMEG_2414 | MSMEG_2416 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Conserved hypothetical protein. | 0.884 |
coaD | ABK76183.1 | MSMEG_2414 | MSMEG_2413 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative methyltransferase; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095. | 0.990 |
coaD | coaA | MSMEG_2414 | MSMEG_5252 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554. | 0.990 |
coaD | coaBC | MSMEG_2414 | MSMEG_3054 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.994 |