STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clgRTranscriptional regulator, xre family; Probably controls the response to vancomycin treatment; vancomycin induces expression of the clp regulon (clpP1, clpP2 and clpC1) (112 aa)    
Predicted Functional Partners:
clpC
Atp-dependent clp protease atp-binding subunit clpc; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Degrades anti-sigma-E factor RseA in the presence of ClpP2 (Probable)
   
 
 0.807
MSMEI_2630
annotation not available
  
  
 0.806
MSMEI_5183
annotation not available
  
     0.758
DUTPase
annotation not available
  
    0.755
MSMEI_3558
annotation not available
  
   
 0.744
MSMEI_2629
annotation not available
  
  
 0.737
rpoZ
Dna-directed rna polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
  
     0.737
whiB1
Whib family transcriptional regulator, redox-sensing transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
  
   
 0.733
nucS
Hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
  
     0.726
secG
Protein-export membrane protein (translocase subunit) secg; Involved in protein export. Participates in an early event of protein translocation
  
     0.723
Your Current Organism:
Mycobacterium smegmatis MC2155
NCBI taxonomy Id: 246196
Other names: M. smegmatis str. MC2 155, Mycobacterium smegmatis MC2 155, Mycobacterium smegmatis str. MC2 155, Mycobacterium smegmatis strain MC2 155
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