node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK72850.1 | ABK74501.1 | MSMEG_5121 | MSMEG_6197 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | 0.621 |
ABK72850.1 | asd | MSMEG_5121 | MSMEG_6256 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.623 |
ABK72850.1 | dapA | MSMEG_5121 | MSMEG_2684 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.557 |
ABK72850.1 | dapB-3 | MSMEG_5121 | MSMEG_2664 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.798 |
ABK72850.1 | dapD | MSMEG_5121 | MSMEG_5104 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.917 |
ABK72850.1 | dapE | MSMEG_5121 | MSMEG_5103 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. | 0.955 |
ABK72850.1 | dapF | MSMEG_5121 | MSMEG_2735 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.898 |
ABK72850.1 | hflX | MSMEG_5121 | MSMEG_2736 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.442 |
ABK72850.1 | lysA | MSMEG_5121 | MSMEG_4958 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.867 |
ABK74501.1 | ABK72850.1 | MSMEG_6197 | MSMEG_5121 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | 0.621 |
ABK74501.1 | asd | MSMEG_6197 | MSMEG_6256 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.668 |
ABK74501.1 | dapA | MSMEG_6197 | MSMEG_2684 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.646 |
ABK74501.1 | dapB-3 | MSMEG_6197 | MSMEG_2664 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.649 |
ABK74501.1 | dapD | MSMEG_6197 | MSMEG_5104 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.463 |
ABK74501.1 | dapE | MSMEG_6197 | MSMEG_5103 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. | 0.406 |
ABK74501.1 | dapF | MSMEG_6197 | MSMEG_2735 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.964 |
ABK74501.1 | lysA | MSMEG_6197 | MSMEG_4958 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.926 |
ABK74501.1 | murE | MSMEG_6197 | MSMEG_4232 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.909 |
asd | ABK72850.1 | MSMEG_6256 | MSMEG_5121 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | 0.623 |
asd | ABK74501.1 | MSMEG_6256 | MSMEG_6197 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. | 0.668 |