node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK71738.1 | ABK72550.1 | MSMEG_1621 | MSMEG_1701 | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.933 |
ABK71738.1 | ABK72836.1 | MSMEG_1621 | MSMEG_4270 | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | Adenosine kinase; Identified by match to protein family HMM PF00294. | 0.921 |
ABK71738.1 | apt | MSMEG_1621 | MSMEG_2964 | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.961 |
ABK71738.1 | hpt | MSMEG_1621 | MSMEG_6110 | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.934 |
ABK72550.1 | ABK71738.1 | MSMEG_1701 | MSMEG_1621 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | 0.933 |
ABK72550.1 | ABK72836.1 | MSMEG_1701 | MSMEG_4270 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenosine kinase; Identified by match to protein family HMM PF00294. | 0.940 |
ABK72550.1 | apt | MSMEG_1701 | MSMEG_2964 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.972 |
ABK72550.1 | guaA | MSMEG_1701 | MSMEG_1610 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.633 |
ABK72550.1 | hpt | MSMEG_1701 | MSMEG_6110 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.955 |
ABK72550.1 | mtaP | MSMEG_1701 | MSMEG_0990 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.625 |
ABK72836.1 | ABK71738.1 | MSMEG_4270 | MSMEG_1621 | Adenosine kinase; Identified by match to protein family HMM PF00294. | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156. | 0.921 |
ABK72836.1 | ABK72550.1 | MSMEG_4270 | MSMEG_1701 | Adenosine kinase; Identified by match to protein family HMM PF00294. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.940 |
ABK72836.1 | adk | MSMEG_4270 | MSMEG_1484 | Adenosine kinase; Identified by match to protein family HMM PF00294. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.956 |
ABK72836.1 | apt | MSMEG_4270 | MSMEG_2964 | Adenosine kinase; Identified by match to protein family HMM PF00294. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.968 |
ABK72836.1 | mtaP | MSMEG_4270 | MSMEG_0990 | Adenosine kinase; Identified by match to protein family HMM PF00294. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.621 |
ABK72836.1 | purB | MSMEG_4270 | MSMEG_5847 | Adenosine kinase; Identified by match to protein family HMM PF00294. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.949 |
adk | ABK72836.1 | MSMEG_1484 | MSMEG_4270 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenosine kinase; Identified by match to protein family HMM PF00294. | 0.956 |
adk | apt | MSMEG_1484 | MSMEG_2964 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.965 |
adk | gmk | MSMEG_1484 | MSMEG_3051 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.925 |
adk | guaA | MSMEG_1484 | MSMEG_1610 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.625 |