STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derKDihydroxyacetone kinase; Catalyzes the phosphorylation of D-erythrulose to D- erythrulose-4P. Involved in the degradation pathways of erythritol and D-threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source. (580 aa)    
Predicted Functional Partners:
ABK74411.1
Multiphosphoryl transfer protein (MTP); Identified by match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF03610; match to protein family HMM PF05524; match to protein family HMM TIGR01003; match to protein family HMM TIGR01417; match to protein family HMM TIGR02364; Belongs to the PEP-utilizing enzyme family.
 
 
 0.927
derI1
Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of erythritol and D- threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family.
 
  
 0.874
dthD
Short chain dehydrogenase; Catalyzes the NAD-dependent reversible oxidation of D- threitol. Involved in the degradation pathway of D-threitol, that allows M.smegmatis to grow on this compound as the sole carbon source. Does not catalyze the oxidation of xylitol, L-sorbitol, and L-sorbose. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.854
eltD
Arabitol-phosphate dehydrogenase; Catalyzes the NAD-dependent reversible oxidation of erythritol and L-threitol. Involved in the degradation pathways of erythritol and L-threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source.
 
 
 0.826
ABK72737.1
Muconate cycloisomerase; Identified by match to protein family HMM PF01188; match to protein family HMM PF02746; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
   
  
 0.824
eltP
Maltose/maltodextrin-binding protein; Part of an ABC transporter complex involved in erythritol/L- threitol import. Binds erythritol and L-threitol. Functions in the transport for the degradation pathways of erythritol and L-threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the bacterial solute-binding protein 1 family.
 
  
 0.808
ABK74533.1
Transporter; Identified by match to protein family HMM PF00528.
  
  
 0.797
ABK73005.1
ABC transporter, permease protein; Identified by match to protein family HMM PF00528.
  
  
 0.795
ABK74542.1
Putative sugar ABC transporter ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF03459; Belongs to the ABC transporter superfamily.
  
  
 0.795
ABK74836.1
SN-glycerol-3-phosphate ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; Belongs to the ABC transporter superfamily.
  
  
 0.790
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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