node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70694.1 | ABK72053.1 | MSMEG_4240 | MSMEG_1133 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Bifunctional short chain isoprenyl diphosphate synthase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.930 |
ABK70694.1 | dxr | MSMEG_4240 | MSMEG_2578 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.454 |
ABK70694.1 | uppS | MSMEG_4240 | MSMEG_4490 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) in the cis configuration with (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP) generating the 50 carbon product trans,polycis-decaprenyl diphosphate. When (2E,6E)-farnesyl diphosphate (E-FPP or EE-FPP) is used in vitro, both primary products decaprenyl diphosphate and heptaprenyl diphosphate are synthesized. It is probably due to the fact that M.smegmatis synthesizes both (2E,6E,10E)- geranylgeranyl diphosphate (EEE-GGPP) and (2E,6E,10Z)-geranylgeranyl diphosphate (EEZ-GGPP). Can als [...] | 0.809 |
ABK70694.1 | uppS-2 | MSMEG_4240 | MSMEG_5256 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl diphosphate (E-GPP) generating the 15 carbon product (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP). Z-FPP is the precursor of decaprenyl diphosphate, which has a central role in the biosynthesis of the mycobacterial cell wall. | 0.976 |
ABK72053.1 | ABK70694.1 | MSMEG_1133 | MSMEG_4240 | Bifunctional short chain isoprenyl diphosphate synthase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.930 |
ABK72053.1 | uppS | MSMEG_1133 | MSMEG_4490 | Bifunctional short chain isoprenyl diphosphate synthase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) in the cis configuration with (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP) generating the 50 carbon product trans,polycis-decaprenyl diphosphate. When (2E,6E)-farnesyl diphosphate (E-FPP or EE-FPP) is used in vitro, both primary products decaprenyl diphosphate and heptaprenyl diphosphate are synthesized. It is probably due to the fact that M.smegmatis synthesizes both (2E,6E,10E)- geranylgeranyl diphosphate (EEE-GGPP) and (2E,6E,10Z)-geranylgeranyl diphosphate (EEZ-GGPP). Can als [...] | 0.805 |
ABK72053.1 | uppS-2 | MSMEG_1133 | MSMEG_5256 | Bifunctional short chain isoprenyl diphosphate synthase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl diphosphate (E-GPP) generating the 15 carbon product (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP). Z-FPP is the precursor of decaprenyl diphosphate, which has a central role in the biosynthesis of the mycobacterial cell wall. | 0.884 |
ABK72107.1 | ABK73645.1 | MSMEG_4492 | MSMEG_4488 | Amidase; Identified by match to protein family HMM PF01425; Belongs to the amidase family. | Identified by match to protein family HMM PF00293. | 0.638 |
ABK72107.1 | ABK75842.1 | MSMEG_4492 | MSMEG_4489 | Amidase; Identified by match to protein family HMM PF01425; Belongs to the amidase family. | Conserved hypothetical protein. | 0.798 |
ABK72107.1 | cdsA | MSMEG_4492 | MSMEG_2543 | Amidase; Identified by match to protein family HMM PF01425; Belongs to the amidase family. | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family. | 0.434 |
ABK72107.1 | recO | MSMEG_4492 | MSMEG_4491 | Amidase; Identified by match to protein family HMM PF01425; Belongs to the amidase family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.822 |
ABK72107.1 | uppS | MSMEG_4492 | MSMEG_4490 | Amidase; Identified by match to protein family HMM PF01425; Belongs to the amidase family. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) in the cis configuration with (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP) generating the 50 carbon product trans,polycis-decaprenyl diphosphate. When (2E,6E)-farnesyl diphosphate (E-FPP or EE-FPP) is used in vitro, both primary products decaprenyl diphosphate and heptaprenyl diphosphate are synthesized. It is probably due to the fact that M.smegmatis synthesizes both (2E,6E,10E)- geranylgeranyl diphosphate (EEE-GGPP) and (2E,6E,10Z)-geranylgeranyl diphosphate (EEZ-GGPP). Can als [...] | 0.809 |
ABK73645.1 | ABK72107.1 | MSMEG_4488 | MSMEG_4492 | Identified by match to protein family HMM PF00293. | Amidase; Identified by match to protein family HMM PF01425; Belongs to the amidase family. | 0.638 |
ABK73645.1 | ABK75842.1 | MSMEG_4488 | MSMEG_4489 | Identified by match to protein family HMM PF00293. | Conserved hypothetical protein. | 0.956 |
ABK73645.1 | recO | MSMEG_4488 | MSMEG_4491 | Identified by match to protein family HMM PF00293. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.836 |
ABK73645.1 | uppS | MSMEG_4488 | MSMEG_4490 | Identified by match to protein family HMM PF00293. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) in the cis configuration with (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP) generating the 50 carbon product trans,polycis-decaprenyl diphosphate. When (2E,6E)-farnesyl diphosphate (E-FPP or EE-FPP) is used in vitro, both primary products decaprenyl diphosphate and heptaprenyl diphosphate are synthesized. It is probably due to the fact that M.smegmatis synthesizes both (2E,6E,10E)- geranylgeranyl diphosphate (EEE-GGPP) and (2E,6E,10Z)-geranylgeranyl diphosphate (EEZ-GGPP). Can als [...] | 0.852 |
ABK75842.1 | ABK72107.1 | MSMEG_4489 | MSMEG_4492 | Conserved hypothetical protein. | Amidase; Identified by match to protein family HMM PF01425; Belongs to the amidase family. | 0.798 |
ABK75842.1 | ABK73645.1 | MSMEG_4489 | MSMEG_4488 | Conserved hypothetical protein. | Identified by match to protein family HMM PF00293. | 0.956 |
ABK75842.1 | recO | MSMEG_4489 | MSMEG_4491 | Conserved hypothetical protein. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.954 |
ABK75842.1 | uppS | MSMEG_4489 | MSMEG_4490 | Conserved hypothetical protein. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) in the cis configuration with (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP) generating the 50 carbon product trans,polycis-decaprenyl diphosphate. When (2E,6E)-farnesyl diphosphate (E-FPP or EE-FPP) is used in vitro, both primary products decaprenyl diphosphate and heptaprenyl diphosphate are synthesized. It is probably due to the fact that M.smegmatis synthesizes both (2E,6E,10E)- geranylgeranyl diphosphate (EEE-GGPP) and (2E,6E,10Z)-geranylgeranyl diphosphate (EEZ-GGPP). Can als [...] | 0.976 |