STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gdhNAD-glutamate dehydrogenase; Catalyzes the reversible conversion of L-glutamate to 2- oxoglutarate. Highly specific for NAD. (1594 aa)    
Predicted Functional Partners:
glnA-2
Glutamine synthetase, type I; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
     
 0.973
glnA-3
Glutamine synthetase, type I; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation [...]
   
 
 0.962
ABK72054.1
Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.961
glnA
Glutamine synthetase, catalytic domain; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
     
 0.958
garA
Forkhead-associated protein; Involved in regulation of glutamate metabolism. Acts as a phosphorylation-dependent molecular switch that modulates the activities of Kgd and Gdh.
   
 
 0.953
ABK70099.1
Ferredoxin-dependent glutamate synthase 1; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
   
 
 0.946
GltD
Glutamate synthase, NADH/nadph, small subunit; Identified by match to protein family HMM PF01266; match to protein family HMM PF07992; match to protein family HMM TIGR01317.
   
 
 0.931
ABK70243.1
Ferredoxin-dependent glutamate synthase 1; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
   
 
 0.930
GltD-2
Glutamate synthase, small subunit; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317.
   
 
 0.920
ABK70552.1
Gamma-glutamylisopropylamide synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
   
 
 0.919
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.