node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK73517.1 | ABK74179.1 | MSMEG_4907 | MSMEG_4904 | Identified by match to protein family HMM PF01398. | Identified by match to protein family HMM PF01694. | 0.857 |
ABK73517.1 | ABK74504.1 | MSMEG_4907 | MSMEG_4906 | Identified by match to protein family HMM PF01398. | Identified by match to protein family HMM PF02597. | 0.990 |
ABK73517.1 | cysM | MSMEG_4907 | MSMEG_4905 | Identified by match to protein family HMM PF01398. | Cysteine synthase B; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136. | 0.992 |
ABK73517.1 | murI | MSMEG_4907 | MSMEG_4903 | Identified by match to protein family HMM PF01398. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.864 |
ABK73517.1 | rdgB | MSMEG_4907 | MSMEG_4899 | Identified by match to protein family HMM PF01398. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.760 |
ABK74179.1 | ABK73517.1 | MSMEG_4904 | MSMEG_4907 | Identified by match to protein family HMM PF01694. | Identified by match to protein family HMM PF01398. | 0.857 |
ABK74179.1 | ABK74504.1 | MSMEG_4904 | MSMEG_4906 | Identified by match to protein family HMM PF01694. | Identified by match to protein family HMM PF02597. | 0.872 |
ABK74179.1 | cysM | MSMEG_4904 | MSMEG_4905 | Identified by match to protein family HMM PF01694. | Cysteine synthase B; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136. | 0.922 |
ABK74179.1 | murI | MSMEG_4904 | MSMEG_4903 | Identified by match to protein family HMM PF01694. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.933 |
ABK74179.1 | rdgB | MSMEG_4904 | MSMEG_4899 | Identified by match to protein family HMM PF01694. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.632 |
ABK74504.1 | ABK73517.1 | MSMEG_4906 | MSMEG_4907 | Identified by match to protein family HMM PF02597. | Identified by match to protein family HMM PF01398. | 0.990 |
ABK74504.1 | ABK74179.1 | MSMEG_4906 | MSMEG_4904 | Identified by match to protein family HMM PF02597. | Identified by match to protein family HMM PF01694. | 0.872 |
ABK74504.1 | cysM | MSMEG_4906 | MSMEG_4905 | Identified by match to protein family HMM PF02597. | Cysteine synthase B; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136. | 0.999 |
ABK74504.1 | murI | MSMEG_4906 | MSMEG_4903 | Identified by match to protein family HMM PF02597. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.842 |
ABK74504.1 | rdgB | MSMEG_4906 | MSMEG_4899 | Identified by match to protein family HMM PF02597. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.559 |
alr | murD | MSMEG_1575 | MSMEG_4229 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.819 |
alr | murG | MSMEG_1575 | MSMEG_4227 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.815 |
alr | murI | MSMEG_1575 | MSMEG_4903 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.936 |
alr | rdgB | MSMEG_1575 | MSMEG_4899 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.441 |
cysM | ABK73517.1 | MSMEG_4905 | MSMEG_4907 | Cysteine synthase B; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136. | Identified by match to protein family HMM PF01398. | 0.992 |