node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69915.1 | hflX | MSMEG_3480 | MSMEG_2736 | Streptomycin 6-kinase (Streptidine kinase) (Streptomycin6-phosphotransferase) (APH(6)); Identified by match to protein family HMM PF04655. | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.759 |
ABK69915.1 | hrpA | MSMEG_3480 | MSMEG_6587 | Streptomycin 6-kinase (Streptidine kinase) (Streptomycin6-phosphotransferase) (APH(6)); Identified by match to protein family HMM PF04655. | ATP-dependent helicase HrpA; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM PF07717; match to protein family HMM TIGR01967. | 0.818 |
ABK69915.1 | vgb | MSMEG_3480 | MSMEG_4914 | Streptomycin 6-kinase (Streptidine kinase) (Streptomycin6-phosphotransferase) (APH(6)); Identified by match to protein family HMM PF04655. | Virginiamycin B hydrolase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.601 |
ABK70699.1 | lfrR | MSMEG_2984 | MSMEG_6223 | Putative hydrolase; Identified by match to protein family HMM PF00561. | TetR family protein transcriptional repressor LfrR; Represses the transcription of the lfrRA operon by binding directly to the promoter region of lfrR-lfrA. Binds specifically to a 143-bp region upstream of the lfrR gene. | 0.404 |
ABK70699.1 | vgb | MSMEG_2984 | MSMEG_4914 | Putative hydrolase; Identified by match to protein family HMM PF00561. | Virginiamycin B hydrolase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.543 |
ABK72491.1 | glgB | MSMEG_4915 | MSMEG_4918 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | 0.998 |
ABK72491.1 | glgE | MSMEG_4915 | MSMEG_4916 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. | 0.964 |
ABK72491.1 | vgb | MSMEG_4915 | MSMEG_4914 | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | Virginiamycin B hydrolase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.807 |
glgB | ABK72491.1 | MSMEG_4918 | MSMEG_4915 | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | 0.998 |
glgB | glgE | MSMEG_4918 | MSMEG_4916 | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. | 0.999 |
glgB | vgb | MSMEG_4918 | MSMEG_4914 | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | Virginiamycin B hydrolase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.578 |
glgE | ABK72491.1 | MSMEG_4916 | MSMEG_4915 | Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. | Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. | 0.964 |
glgE | glgB | MSMEG_4916 | MSMEG_4918 | Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | 0.999 |
glgE | vgb | MSMEG_4916 | MSMEG_4914 | Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. | Virginiamycin B hydrolase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.578 |
hflX | ABK69915.1 | MSMEG_2736 | MSMEG_3480 | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Streptomycin 6-kinase (Streptidine kinase) (Streptomycin6-phosphotransferase) (APH(6)); Identified by match to protein family HMM PF04655. | 0.759 |
hflX | hrpA | MSMEG_2736 | MSMEG_6587 | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | ATP-dependent helicase HrpA; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM PF07717; match to protein family HMM TIGR01967. | 0.705 |
hflX | smpB | MSMEG_2736 | MSMEG_2091 | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.538 |
hflX | vgb | MSMEG_2736 | MSMEG_4914 | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Virginiamycin B hydrolase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.620 |
hrpA | ABK69915.1 | MSMEG_6587 | MSMEG_3480 | ATP-dependent helicase HrpA; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM PF07717; match to protein family HMM TIGR01967. | Streptomycin 6-kinase (Streptidine kinase) (Streptomycin6-phosphotransferase) (APH(6)); Identified by match to protein family HMM PF04655. | 0.818 |
hrpA | hflX | MSMEG_6587 | MSMEG_2736 | ATP-dependent helicase HrpA; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM PF07717; match to protein family HMM TIGR01967. | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.705 |