node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69794.1 | ABK73626.1 | MSMEG_5725 | MSMEG_6257 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Asparate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. | 0.520 |
ABK69794.1 | argD | MSMEG_5725 | MSMEG_3773 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Acetylornithine aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM PF01212; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.915 |
ABK69794.1 | asd | MSMEG_5725 | MSMEG_6256 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.534 |
ABK69794.1 | dapD | MSMEG_5725 | MSMEG_5104 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.971 |
ABK69794.1 | dapE | MSMEG_5725 | MSMEG_5103 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. | 0.957 |
ABK69794.1 | dapF | MSMEG_5725 | MSMEG_2735 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.602 |
ABK69794.1 | murC | MSMEG_5725 | MSMEG_4226 | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.406 |
ABK72850.1 | ABK73626.1 | MSMEG_5121 | MSMEG_6257 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Asparate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. | 0.754 |
ABK72850.1 | asd | MSMEG_5121 | MSMEG_6256 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.623 |
ABK72850.1 | dapB-3 | MSMEG_5121 | MSMEG_2664 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.798 |
ABK72850.1 | dapD | MSMEG_5121 | MSMEG_5104 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.917 |
ABK72850.1 | dapE | MSMEG_5121 | MSMEG_5103 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. | 0.955 |
ABK72850.1 | dapF | MSMEG_5121 | MSMEG_2735 | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.898 |
ABK73626.1 | ABK69794.1 | MSMEG_6257 | MSMEG_5725 | Asparate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. | PLP-dependent aminotransferases; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212. | 0.520 |
ABK73626.1 | ABK72850.1 | MSMEG_6257 | MSMEG_5121 | Asparate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. | Aminotransferase, classes I and II; Identified by similarity to SP:P77434; match to protein family HMM PF00155. | 0.754 |
ABK73626.1 | asd | MSMEG_6257 | MSMEG_6256 | Asparate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.999 |
ABK73626.1 | dapB-3 | MSMEG_6257 | MSMEG_2664 | Asparate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.914 |
ABK73626.1 | dapD | MSMEG_6257 | MSMEG_5104 | Asparate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. | Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.845 |
ABK73626.1 | dapE | MSMEG_6257 | MSMEG_5103 | Asparate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. | 0.714 |
ABK73626.1 | dapF | MSMEG_6257 | MSMEG_2735 | Asparate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.859 |