STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
mcaMycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetyl-cysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics. Activity is specific for the mycothiol moiety. (288 aa)    
Predicted Functional Partners:
cysS
cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins.
 
  
 0.960
mshA
Conserved hypothetical protein; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway; Belongs to the glycosyltransferase group 1 family. MshA subfamily.
 
  
 0.916
ABK69866.1
Conserved hypothetical protein.
  
    0.897
ABK71344.1
Conserved hypothetical protein; Identified by match to protein family HMM PF03190.
  
    0.872
ABK72519.1
Conserved hypothetical protein.
  
   
 0.830
ABK71565.1
Conserved hypothetical protein, putative; Identified by match to protein family HMM PF01323.
 
    0.794
ABK74463.1
Conserved hypothetical protein.
  
    0.786
ABK74818.1
Conserved hypothetical protein.
  
    0.759
ABK73925.1
Steroid delta-isomerase; Identified by match to protein family HMM PF02136.
  
    0.755
ABK72185.1
Conserved hypothetical protein.
  
    0.661
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.