STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
kdpAK+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (556 aa)    
Predicted Functional Partners:
kdpB
K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
 
 0.999
kdpC
Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
 
 0.999
ABK75585.1
Sensor protein KdpD; Identified by match to protein family HMM PF00512; match to protein family HMM PF00582; match to protein family HMM PF02518; match to protein family HMM PF02702.
 
  
 0.988
ABK74820.1
KDP operon transcriptional regulatory protein KdpE; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
  
 0.980
ABK74250.1
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.956
ABK71614.1
Sensor protein KdpD; Identified by match to protein family HMM PF00512; match to protein family HMM PF00582; match to protein family HMM PF02518; match to protein family HMM PF02702.
 
  
 0.915
pknG
Serine/threonine protein kinase; Identified by match to protein family HMM PF00069; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
  
 0.677
ABK73614.1
4-amino-4-deoxychorismate lyase.
   
  
 0.665
mprB
Sensor histidine kinase; Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. In response to environmental signals MprB acts as both a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to MprA, and a protein phosphatase that dephosphorylates phospho-MprA (By similarity).
  
  
 0.576
ABK75795.1
Two-component system sensor kinase; Identified by match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF07730; match to protein family HMM TIGR00229.
  
  
 0.573
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.