node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70064.1 | ABK70151.1 | MSMEG_5018 | MSMEG_4279 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | 0.426 |
ABK70064.1 | ABK70370.1 | MSMEG_5018 | MSMEG_5458 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | 0.829 |
ABK70064.1 | ABK71907.1 | MSMEG_5018 | MSMEG_3578 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Putative cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672. | 0.775 |
ABK70151.1 | ABK70064.1 | MSMEG_4279 | MSMEG_5018 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | 0.426 |
ABK70151.1 | ABK70370.1 | MSMEG_4279 | MSMEG_5458 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | 0.792 |
ABK70151.1 | ABK71907.1 | MSMEG_4279 | MSMEG_3578 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Putative cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672. | 0.900 |
ABK70370.1 | ABK70064.1 | MSMEG_5458 | MSMEG_5018 | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | 0.829 |
ABK70370.1 | ABK70151.1 | MSMEG_5458 | MSMEG_4279 | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | 0.792 |
ABK70370.1 | ABK71532.1 | MSMEG_5458 | MSMEG_5457 | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | 0.816 |
ABK70370.1 | ABK71907.1 | MSMEG_5458 | MSMEG_3578 | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | Putative cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672. | 0.800 |
ABK70370.1 | ABK72096.1 | MSMEG_5458 | MSMEG_3939 | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | Identified by match to protein family HMM PF00582. | 0.722 |
ABK70370.1 | ABK73445.1 | MSMEG_5458 | MSMEG_1411 | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | Identified by match to protein family HMM PF00582. | 0.742 |
ABK70370.1 | pks | MSMEG_5458 | MSMEG_0408 | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801. | 0.758 |
ABK70370.1 | pta | MSMEG_5458 | MSMEG_0783 | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.732 |
ABK70370.1 | saeC | MSMEG_5458 | MSMEG_0046 | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | Conserved hypothetical protein; May be involved in assembly of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Involved in DNA conjugation in recipient (MKD8) strain. | 0.736 |
ABK70370.1 | sir2 | MSMEG_5458 | MSMEG_5175 | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | NAD-dependent deacetylase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | 0.772 |
ABK71532.1 | ABK70370.1 | MSMEG_5457 | MSMEG_5458 | Shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01488. | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | 0.816 |
ABK71907.1 | ABK70064.1 | MSMEG_3578 | MSMEG_5018 | Putative cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672. | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | 0.775 |
ABK71907.1 | ABK70151.1 | MSMEG_3578 | MSMEG_4279 | Putative cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672. | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | 0.900 |
ABK71907.1 | ABK70370.1 | MSMEG_3578 | MSMEG_5458 | Putative cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672. | Cyclic nucleotide-binding protein; Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes. | 0.800 |