node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK70164.1 | disA | MSMEG_6078 | MSMEG_6080 | LpqE protein. | Conserved hypothetical protein; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. Belongs to the DisA family. | 0.956 |
ABK70164.1 | ispD | MSMEG_6078 | MSMEG_6076 | LpqE protein. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.471 |
ABK70164.1 | radA | MSMEG_6078 | MSMEG_6079 | LpqE protein. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function (By similarity). Also inhibits the diadenylate cyclase activity of DisA ; Belongs to the Rec [...] | 0.815 |
ABK73029.1 | ABK74084.1 | MSMEG_1941 | MSMEG_4259 | Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily. | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | 0.832 |
ABK73029.1 | ABK75351.1 | MSMEG_1941 | MSMEG_6892 | Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.806 |
ABK73029.1 | disA | MSMEG_1941 | MSMEG_6080 | Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily. | Conserved hypothetical protein; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. Belongs to the DisA family. | 0.610 |
ABK73029.1 | radA | MSMEG_1941 | MSMEG_6079 | Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function (By similarity). Also inhibits the diadenylate cyclase activity of DisA ; Belongs to the Rec [...] | 0.734 |
ABK73029.1 | recA | MSMEG_1941 | MSMEG_2723 | Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily. | Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...] | 0.806 |
ABK73029.1 | uvrC | MSMEG_1941 | MSMEG_3078 | Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.650 |
ABK74084.1 | ABK73029.1 | MSMEG_4259 | MSMEG_1941 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily. | 0.832 |
ABK74084.1 | ABK75351.1 | MSMEG_4259 | MSMEG_6892 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.413 |
ABK74084.1 | radA | MSMEG_4259 | MSMEG_6079 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function (By similarity). Also inhibits the diadenylate cyclase activity of DisA ; Belongs to the Rec [...] | 0.786 |
ABK74084.1 | recA | MSMEG_4259 | MSMEG_2723 | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...] | 0.586 |
ABK75351.1 | ABK73029.1 | MSMEG_6892 | MSMEG_1941 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily. | 0.806 |
ABK75351.1 | ABK74084.1 | MSMEG_6892 | MSMEG_4259 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573. | 0.413 |
ABK75351.1 | radA | MSMEG_6892 | MSMEG_6079 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function (By similarity). Also inhibits the diadenylate cyclase activity of DisA ; Belongs to the Rec [...] | 0.746 |
ABK75351.1 | recA | MSMEG_6892 | MSMEG_2723 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...] | 0.694 |
ABK75351.1 | recX | MSMEG_6892 | MSMEG_2724 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.635 |
disA | ABK70164.1 | MSMEG_6080 | MSMEG_6078 | Conserved hypothetical protein; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. Belongs to the DisA family. | LpqE protein. | 0.956 |
disA | ABK73029.1 | MSMEG_6080 | MSMEG_1941 | Conserved hypothetical protein; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. Belongs to the DisA family. | Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily. | 0.610 |