node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK71134.1 | ABK72375.1 | MSMEG_6388 | MSMEG_6387 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | 0.835 |
ABK71134.1 | ABK72840.1 | MSMEG_6388 | MSMEG_6389 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | 0.999 |
ABK71134.1 | ABK74014.1 | MSMEG_6388 | MSMEG_3879 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Short chain dehydrogenase; Identified by match to protein family HMM PF00106. | 0.479 |
ABK71134.1 | ABK74530.1 | MSMEG_6388 | MSMEG_6372 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Identified by match to protein family HMM PF04138. | 0.806 |
ABK71134.1 | ABK74962.1 | MSMEG_6388 | MSMEG_6401 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Prenyltransferase, UbiA family protein; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5-phosphoribose (DPPR). | 0.650 |
ABK71134.1 | aftA | MSMEG_6388 | MSMEG_6386 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases. It is not able to add an Araf residue to a terminal Galf. | 0.984 |
ABK71134.1 | dprE1 | MSMEG_6388 | MSMEG_6382 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Oxidoreductase, FAD-binding; Component of the DprE1-DprE2 complex that catalyzes the 2- step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl- phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans. DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX). The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'substrate chann [...] | 0.801 |
ABK71134.1 | dprE2 | MSMEG_6388 | MSMEG_6385 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | Putative oxidoreductase in MprA 5'region; Component of the DprE1-DprE2 complex that catalyzes the 2- step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl- phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans. DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX). The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'su [...] | 0.851 |
ABK71134.1 | inhA | MSMEG_6388 | MSMEG_3151 | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | [NADH] enoyl-[acyl-carrier-protein] reductase; Enoyl-ACP reductase of the type II fatty acid syntase (FAS- II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans- enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates (By similarity). The mycobacterial FAS-II system utilizes th [...] | 0.813 |
ABK72375.1 | ABK71134.1 | MSMEG_6387 | MSMEG_6388 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | 0.835 |
ABK72375.1 | ABK72840.1 | MSMEG_6387 | MSMEG_6389 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | 0.698 |
ABK72375.1 | ABK74014.1 | MSMEG_6387 | MSMEG_3879 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Short chain dehydrogenase; Identified by match to protein family HMM PF00106. | 0.504 |
ABK72375.1 | ABK74530.1 | MSMEG_6387 | MSMEG_6372 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Identified by match to protein family HMM PF04138. | 0.895 |
ABK72375.1 | ABK74962.1 | MSMEG_6387 | MSMEG_6401 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Prenyltransferase, UbiA family protein; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5-phosphoribose (DPPR). | 0.723 |
ABK72375.1 | aftA | MSMEG_6387 | MSMEG_6386 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Membrane protein; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases. It is not able to add an Araf residue to a terminal Galf. | 0.994 |
ABK72375.1 | dprE1 | MSMEG_6387 | MSMEG_6382 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Oxidoreductase, FAD-binding; Component of the DprE1-DprE2 complex that catalyzes the 2- step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl- phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans. DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX). The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'substrate chann [...] | 0.919 |
ABK72375.1 | dprE2 | MSMEG_6387 | MSMEG_6385 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Putative oxidoreductase in MprA 5'region; Component of the DprE1-DprE2 complex that catalyzes the 2- step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl- phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans. DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX). The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'su [...] | 0.951 |
ABK72375.1 | inhA | MSMEG_6387 | MSMEG_3151 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | [NADH] enoyl-[acyl-carrier-protein] reductase; Enoyl-ACP reductase of the type II fatty acid syntase (FAS- II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans- enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates (By similarity). The mycobacterial FAS-II system utilizes th [...] | 0.710 |
ABK72840.1 | ABK71134.1 | MSMEG_6389 | MSMEG_6388 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Probable arabinosyltransferase B; Identified by match to protein family HMM PF04602. | 0.999 |
ABK72840.1 | ABK72375.1 | MSMEG_6389 | MSMEG_6387 | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | Probable arabinosyltransferase A; Identified by match to protein family HMM PF04602. | 0.698 |