node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK74343.1 | ABK74424.1 | MSMEG_3576 | MSMEG_4696 | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | Identified by match to protein family HMM PF00128. | 0.934 |
ABK74343.1 | glgB | MSMEG_3576 | MSMEG_4918 | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | 0.964 |
ABK74343.1 | glgC | MSMEG_3576 | MSMEG_5078 | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. | 0.603 |
ABK74343.1 | glgE | MSMEG_3576 | MSMEG_4916 | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. | 0.611 |
ABK74343.1 | glgM | MSMEG_3576 | MSMEG_5080 | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | Glycogen synthase; Involved in the biosynthesis of the maltose-1-phosphate (M1P) building block required for alpha-glucan production by the key enzyme GlgE. Catalyzes the formation of an alpha-1,4 linkage between glucose from ADP-glucose and glucose 1-phosphate (G1P) to yield maltose-1- phosphate (M1P). | 0.520 |
ABK74343.1 | mak | MSMEG_3576 | MSMEG_6514 | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | Trehalose synthase-fused probable maltokinase; Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate (Probable). Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB. | 0.940 |
ABK74343.1 | malQ | MSMEG_3576 | MSMEG_3673 | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | 4-alpha-glucanotransferase; Identified by match to protein family HMM PF02446; match to protein family HMM TIGR00217. | 0.943 |
ABK74343.1 | treS | MSMEG_3576 | MSMEG_6515 | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | Trehalose synthase; Catalyzes the reversible interconversion of maltose and trehalose by transglucosylation. Maltose is the preferred substrate. To a lesser extent, also displays amylase activity, catalyzing the endohydrolysis of (1->4)-alpha-D- glucosidic linkages in glycogen and maltooligosaccharides such as maltoheptaose, to produce maltose which then can be converted to trehalose. TreS plays a key role in the utilization of trehalose for the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Might also functio [...] | 0.939 |
ABK74343.1 | treZ | MSMEG_3576 | MSMEG_3184 | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | Malto-oligosyltrehalose trehalohydrolase; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402. | 0.671 |
ABK74424.1 | ABK74343.1 | MSMEG_4696 | MSMEG_3576 | Identified by match to protein family HMM PF00128. | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | 0.934 |
ABK74424.1 | glgB | MSMEG_4696 | MSMEG_4918 | Identified by match to protein family HMM PF00128. | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | 0.707 |
ABK74424.1 | glgC | MSMEG_4696 | MSMEG_5078 | Identified by match to protein family HMM PF00128. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. | 0.519 |
ABK74424.1 | glgE | MSMEG_4696 | MSMEG_4916 | Identified by match to protein family HMM PF00128. | Alpha-amylase family protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is also able to catalyze the reverse reaction in vitro. Cannot use glucose 1-phosphate as substrate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. | 0.779 |
ABK74424.1 | glgM | MSMEG_4696 | MSMEG_5080 | Identified by match to protein family HMM PF00128. | Glycogen synthase; Involved in the biosynthesis of the maltose-1-phosphate (M1P) building block required for alpha-glucan production by the key enzyme GlgE. Catalyzes the formation of an alpha-1,4 linkage between glucose from ADP-glucose and glucose 1-phosphate (G1P) to yield maltose-1- phosphate (M1P). | 0.446 |
ABK74424.1 | mak | MSMEG_4696 | MSMEG_6514 | Identified by match to protein family HMM PF00128. | Trehalose synthase-fused probable maltokinase; Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate (Probable). Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB. | 0.984 |
ABK74424.1 | malQ | MSMEG_4696 | MSMEG_3673 | Identified by match to protein family HMM PF00128. | 4-alpha-glucanotransferase; Identified by match to protein family HMM PF02446; match to protein family HMM TIGR00217. | 0.955 |
ABK74424.1 | otsA | MSMEG_4696 | MSMEG_5892 | Identified by match to protein family HMM PF00128. | Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Involved in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1- phosphate (M1P), and probably in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to glucose-6-phosphate (Glc-6-P) to form trehalose-6-phosphate. ADP-Glc, CDP-Glc, GDP- Glc and TDP-Glc are also glucosyl donors, however, when the pyrimidine sugar nucleotides (CDP-Glc, TDP-Glc and UDP-Glc) are used as substrates, there is an absolute requirement [...] | 0.469 |
ABK74424.1 | treS | MSMEG_4696 | MSMEG_6515 | Identified by match to protein family HMM PF00128. | Trehalose synthase; Catalyzes the reversible interconversion of maltose and trehalose by transglucosylation. Maltose is the preferred substrate. To a lesser extent, also displays amylase activity, catalyzing the endohydrolysis of (1->4)-alpha-D- glucosidic linkages in glycogen and maltooligosaccharides such as maltoheptaose, to produce maltose which then can be converted to trehalose. TreS plays a key role in the utilization of trehalose for the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Might also functio [...] | 0.947 |
ABK74424.1 | treZ | MSMEG_4696 | MSMEG_3184 | Identified by match to protein family HMM PF00128. | Malto-oligosyltrehalose trehalohydrolase; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402. | 0.783 |
glgB | ABK74343.1 | MSMEG_4918 | MSMEG_3576 | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. | Alpha-amylase 3; Identified by match to protein family HMM PF00128. | 0.964 |