STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lerKDihydroxyacetone kinase; Kinase that has a preference for L-erythrulose, producing L- erythrulose-1P. Involved in the degradation pathway of L-threitol, that allows M.smegmatis to grow on this compound as the sole carbon source. Is also able to phosphorylate D-erythrulose and dihydroxyacetone in vitro. (571 aa)    
Predicted Functional Partners:
ABK74411.1
Multiphosphoryl transfer protein (MTP); Identified by match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF03610; match to protein family HMM PF05524; match to protein family HMM TIGR01003; match to protein family HMM TIGR01417; match to protein family HMM TIGR02364; Belongs to the PEP-utilizing enzyme family.
 
 
 0.927
derI2
Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of L-threitol, D- threitol and erythritol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family.
 
  
 0.768
tpiA-2
Triosephosphate isomerase; Catalyzes the isomerization of L-erythrulose-1P to D- erythrulose-4P. Involved in the degradation pathway of L-threitol, that allows M.smegmatis to grow on this compound as the sole carbon source. Belongs to the triosephosphate isomerase family.
 
  
 0.748
ABK70805.1
Identified by match to protein family HMM PF01261.
 
   
 0.722
ABK69897.1
Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.
  
    0.550
ABK76045.1
3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF01210; match to protein family HMM PF02737; match to protein family HMM PF03446.
 
    0.456
derI1
Ribose 5-phosphate isomerase; Catalyzes the isomerization of D-erythrulose-4P to D- erythrose-4P. Involved in the degradation pathways of erythritol and D- threitol, that allow M.smegmatis to grow on these compounds as the sole carbon source; Belongs to the LacAB/RpiB family.
 
  
 0.436
ABK73673.1
Transport integral membrane protein; Identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
 0.421
ABK72038.1
Glycerol uptake facilitator, MIP channel; Identified by match to protein family HMM PF00230; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
 0.418
ABK71730.1
Helix-turn-helix, Fis-type, putative; Identified by match to protein family HMM PF04397.
  
 
 0.417
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.