STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Identified by similarity to SP:P48247; match to protein family HMM PF00202; match to protein family HMM TIGR00713. (431 aa)    
Predicted Functional Partners:
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.994
hemB
Porphobilinogen synthase; Identified by similarity to SP:P30950; match to protein family HMM PF00490; Belongs to the ALAD family.
 
 
 0.991
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.949
MXAN_3630
Polyketide synthase type I; Identified by similarity to GB:BAB74345.1; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.
    
 0.898
MXAN_3621
Polyketide synthase type I; Identified by similarity to GB:BAB74345.1; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.
    
 0.894
MXAN_4305
Amino acid adenyltransferase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family.
 
    0.841
MXAN_3937
Identified by match to protein family HMM PF00296.
      0.834
hemD
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.821
MXAN_3620
Polyketide synthase type I; Identified by similarity to GB:BAB74345.1; match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.
    
 0.814
MXAN_2339
Siroheme synthase N-terminal domain protein; Identified by match to protein family HMM TIGR01470.
   
 0.783
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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