STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (426 aa)    
Predicted Functional Partners:
kmo
Putative kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
 
 0.998
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
 
  
  0.995
kynA
Putative tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.987
MXAN_0731
Conserved hypothetical protein; Identified by similarity to GB:CAE13727.1.
 
 
 0.983
MXAN_0918
2-amino-3-carboxylmuconate-6-semialdehyde decarboxylase; Identified by similarity to GB:BAC65312.1; match to protein family HMM PF04909.
 
  
 0.950
katB
Catalase KatB; Identified by similarity to SP:Q59635; match to protein family HMM PF00199; Belongs to the catalase family.
   
 
 0.903
katE
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 
 0.903
MXAN_0920
2-aminomuconate deaminase; Identified by similarity to GB:AAK26524.1; match to protein family HMM PF01042.
 
    0.828
MXAN_0921
2-aminomuconic semialdehyde dehydrogenase; Identified by similarity to GB:BAB03533.1; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
 
  
 0.800
MXAN_0915
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106.
   
   0.780
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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