STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIMG_05051Propionyl-CoA carboxylase. (582 aa)    
Predicted Functional Partners:
CIMG_06726
3-methylcrotonyl-CoA carboxylase subunit alpha.
 
 0.997
CIMG05050
Carboxylase:pyruvate/acetyl-CoA/propionyl-CoA.
 
 0.914
CIMG_07858
Biotin-[acetyl-CoA-carboxylase] ligase.
  
 
 0.899
CIMG_09573
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 0.837
CIMG_01357
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.815
CIMG_01245
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 
 0.801
CIMG_01466
4-hydroxyphenylpyruvate dioxygenase.
  
 
 0.781
TCRP
4-hydroxyphenylpyruvate dioxygenase.
  
 
 0.781
CIMG_00827
Acetyl-CoA carboxylase.
   
 0.780
CIMG_00874
Malic enzyme.
  
 
 0.750
Your Current Organism:
Coccidioides immitis RS
NCBI taxonomy Id: 246410
Other names: C. immitis RS
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