Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein (182 aa)
Predicted Functional Partners:
Hypothetical protein (126 aa)
Hypothetical protein (95 aa)
Oxidoreductase (372 aa)
Hypothetical protein (124 aa)
AhpC/TSA family protein (212 aa)
Peroxiredoxin (184 aa)
Bacterioferritin comigratory protein (148 aa)
Hypothetical protein (231 aa)
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (280 aa)