STRINGSTRING
pyrR protein (Gloeobacter violaceus) - STRING interaction network
"pyrR" - Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase in Gloeobacter violaceus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrRBifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (176 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase (329 aa)
 
  0.984
glr1079
Bifunctional orotidine 5’-phosphate decarboxylase/orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (484 aa)
   
 
  0.978
pyrF
Orotidine 5’-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5’- monophosphate (OMP) to uridine 5’-monophosphate (UMP) (237 aa)
   
 
  0.960
gll3822
Dihydroorotase (407 aa)
 
  0.948
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP (235 aa)
         
  0.912
panC/cmk
Bifunctional pantoate ligase/cytidylate kinase (515 aa)
       
    0.901
gll2528
Cytosine deaminase (428 aa)
         
    0.900
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates (263 aa)
         
    0.900
glr3669
Dihydroorotase (443 aa)
 
 
  0.873
gll0063
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (222 aa)
         
  0.870
Your Current Organism:
Gloeobacter violaceus
NCBI taxonomy Id: 251221
Other names: G. violaceus, G. violaceus PCC 7421, Gloeobacter, Gloeobacter violaceus, Gloeobacter violaceus ATCC 29082, Gloeobacter violaceus PCC 7421, Gloeobacter violaceus str. PCC 7421, Gloeobacter violaceus strain PCC 7421, Gloeobacterales, Gloeobacterales Cavalier-Smith 2002, Gloeobacteria, Gloeobacteria Cavalier-Smith 2002
Server load: low (9%) [HD]