Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Hypothetical protein (928 aa)
Predicted Functional Partners:
Hypothetical protein (739 aa)
Hypothetical protein (362 aa)
Hypothetical protein (307 aa)
Hypothetical protein (179 aa)
Hypothetical protein (100 aa)
Hypothetical protein (972 aa)
Hypothetical protein (602 aa)
Hypothetical protein (596 aa)
Aspartate-semialdehyde dehydrogenase (322 aa)
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (531 aa)