Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Hypothetical protein (203 aa)
Predicted Functional Partners:
Thiol-disulfide interchange protein DsbD-like protein (708 aa)
Ferredoxin-dependent glutamate synthase (1534 aa)
AhpC/TSA family protein (212 aa)
Peroxiredoxin (184 aa)
Bacterioferritin comigratory protein (148 aa)
Dihydrolipoamide dehydrogenase (459 aa)
Hypothetical protein (450 aa)
Glutathione reductase (450 aa)
Mercuric reductase (507 aa)
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (221 aa)