STRINGSTRING
hemD protein (Gloeobacter violaceus) - STRING interaction network
"hemD" - Uroporphyrinogen III synthase/methyltransferase in Gloeobacter violaceus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemDUroporphyrinogen III synthase/methyltransferase (508 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (328 aa)
  0.998
hemB
Delta-aminolevulinic acid dehydratase (327 aa)
 
 
  0.997
hemL
Glutamate-1-semialdehyde aminotransferase (432 aa)
 
 
  0.981
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (430 aa)
 
 
  0.979
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (347 aa)
   
 
  0.975
nirA
Ferredoxin-nitrite reductase (518 aa)
 
 
  0.967
cobI
Precorrin-2 methyltransferase (239 aa)
       
  0.967
cobA
uroporphyrin-III C-methyltransferase (246 aa)
 
 
0.947
sir
Sulfite reductase subunit beta (560 aa)
 
 
  0.937
gll0378
precorrin-6Y methylase (409 aa)
   
   
  0.901
Your Current Organism:
Gloeobacter violaceus
NCBI taxonomy Id: 251221
Other names: G. violaceus, G. violaceus PCC 7421, Gloeobacter, Gloeobacter violaceus, Gloeobacter violaceus ATCC 29082, Gloeobacter violaceus PCC 7421, Gloeobacter violaceus str. PCC 7421, Gloeobacter violaceus strain PCC 7421, Gloeobacterales, Gloeobacterales Cavalier-Smith 2002, Gloeobacteria, Gloeobacteria Cavalier-Smith 2002
Server load: low (10%) [HD]