STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chro_3323PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR012999:IPR013027:IPR004099:IPR000815; KEGG: cyh:Cyan8802_0963 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Pyridine nucleotide-disulphide oxidoreductase dimerisation region. (474 aa)    
Predicted Functional Partners:
Chro_1978
Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR003016:IPR000276:IPR000089:IPR004167:IPR 001078; KEGG: npu:Npun_F6414 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain-containing protein of components of vari [...]
 0.995
Chro_1465
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.969
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.903
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.801
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.742
Chro_4728
PFAM: Biotin/lipoate A/B protein ligase family; COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143; KEGG: npu:Npun_F6359 biotin/lipoate A/B protein ligase; PFAM: biotin/lipoate A/B protein ligase; SPTR: Biotin/lipoate A/B protein ligase.
  
 
 0.698
Chro_3322
Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: ana:all0250 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein.
     
 0.651
Chro_1225
NHL repeat containing protein; PFAM: AhpC/TSA family; InterPro IPR000866:IPR001258:IPR017936; KEGG: npu:Npun_R3814 redoxin domain-containing protein; PFAM: NHL repeat containing protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Redoxin domain protein.
   
 0.650
Chro_2773
KEGG: ava:Ava_4284 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 0.642
Chro_4564
KEGG: npu:Npun_R3552 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 0.642
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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