STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0392Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 32.9 kDa protein Rv0495c or MT0515 or MTCY20G9.21c SW:Y495_MYCTU (Q11160) (296 aa) fasta scores: E(): 3.6e-25, 44.07% id in 270 aa. (289 aa)    
Predicted Functional Partners:
DIP2046
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 32.6 kDa protein Rv0428c or MT0443 or MTCY22G10.25c SWALL:P96274 (EMBL:Z84724) (302 aa) fasta scores: E(): 2.7e-22, 34.53% id in 304 aa, and to Caulobacter crescentus acetyltransferase, GNAT family CC2209 SWALL:Q9A685 (EMBL:AE005892) (207 aa) fasta scores: E(): 2.4e-06, 30.76% id in 208 aa.
  
     0.707
DIP0393
Putative membrane protein; No significant database matches.
       0.637
DIP2176
Similar to Mycobacterium leprae putative integral membrane protein Ml2581 TR:Q9CD18 (EMBL:AL583926) (427 aa) fasta scores: E(): 8.6e-14, 27.79% id in 367 aa.
  
     0.607
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.600
DIP1157
Conserved hypothetical protein; N-terminal region similar to Streptomyces coelicolor hypothetical 18.8 kDa protein SC9H11.26c SWALL:Q9KYL5 (EMBL:AL356592) (177 aa) fasta scores: E(): 9.8e-11, 35.13% id in 148 aa. Note: Possible colied-coil region at C-terminal domain from residue 242 till the end.
  
     0.591
DIP0395
Putative DNA-binding (excisionase) protein; Similar to Mycobacterium leprae B2168_C1_172 ML2429 TR:Q49828 (EMBL:U00018) (86 aa) fasta scores: E(): 7.6e-16, 80% id in 55 aa.
 
     0.583
DIP1447
Putative membrane protein; Low similarity to Mycobacterium tuberculosis CDC1551 hypothetical 19.3 kDa protein MT2802.1 TR:AAK47121 (EMBL:AE007108) (180 aa) fasta scores: E(): 3.3e-07, 25.68% id in 183 aa.
  
     0.484
DIP1802
Similar to Halobacterium sp hypothetical protein VNG1407C TR:Q9HPZ1 (EMBL:AE005058) (132 aa) fasta scores: E(): 2.8e-09, 37.06% id in 116 aa, and to Pseudomonas aeruginosa hypothetical protein PA2801 TR:Q9I042 (EMBL:AE004707) (134 aa) fasta scores: E(): 4e-07, 35.38% id in 130 aa.
  
     0.458
DIP2182
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 26.2 kDa protein Rv0207c or MT0217 or MTCY08D5.02c TR:AAK44438 (EMBL:Z92669) (244 aa) fasta scores: E(): 8.6e-51, 64.03% id in 203 aa.
  
     0.447
DIP2174
Similar to Mycobacterium leprae possible integral membrane protein ML2570 TR:Q9CD19 (EMBL:AL583926) (1405 aa) fasta scores: E(): 2.5e-17, 37.3% id in 823 aa, and to Mycobacterium tuberculosis hypothetical 146.3 kDa protein Rv0236c or MT0247 or MTV034.01c or MTV034.02c or MTCY08D5.32c TR:AAK44467 (EMBL:Z92669) (1400 aa) fasta scores: E(): 7.4e-17, 38.32% id in 822 aa. ORF overlaps with convergent downstream ORF.
  
     0.445
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (70%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.