STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0877Similar to Streptomyces coelicolor putative ABC transporter ATP-binding subunit SCE66.26c TR:Q9K3R7 (EMBL:AL359989) (604 aa) fasta scores: E(): 2.3e-97, 54.75% id in 610 aa. (602 aa)    
Predicted Functional Partners:
rsmA
Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.899
ispE
Putative kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
  
  
 0.855
DIP0878
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 12.0 kDa protein Rv1117 or MTCY22G8.06 TR:O06569 (EMBL:Z95585) (107 aa) fasta scores: E(): 3.6e-13, 43.92% id in 107 aa.
       0.807
DIP0874
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 38.1 kDa protein Rv1009 or MTCI237.26 TR:O05594 (EMBL:Z94752) (362 aa) fasta scores: E(): 1.8e-39, 38.71% id in 372 aa.
     
 0.796
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.700
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
   0.698
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.697
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
   0.697
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.696
rpmH
50S ribosomal protein L34; Similar to Mycobacterium paratuberculosis 50S ribosomal protein L34 RpmH SW:RL34_MYCPA (Q9L7L8) (47 aa) fasta scores: E(): 2.9e-15, 80.85% id in 47 aa, to Streptomyces bikiniensis 50S ribosomal protein L34 RpmH SW:RL34_STRBI (P25820) (45 aa) fasta scores: E(): 2.2e-13, 81.39% id in 43 aa, and to Escherichia coli 50S ribosomal protein L34 Rpmh or SsaF or RimA or B3703 or Z5194 or ECS4638 or STM3839 SW:RL34_ECOLI (P02437) (46 aa) fasta scores: E(): 1.1e-07, 59.52% id in 42 aa; Belongs to the bacterial ribosomal protein bL34 family.
   
   0.690
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.