STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroHSimilar to Streptomyces coelicolor phospho-2-dehydro-3-deoxyheptonate aldolase AroH or SC6E10.09c SW:AROF_STRCO (P80574) (449 aa) fasta scores: E(): 2.4e-92, 55.6% id in 437 aa, and to Mycobacterium tuberculosis CDC1551 phospho-2-dehydro-3-deoxyheptonate aldolase, putative MT2234 TR:AAK46519 (EMBL:AE007070) (462 aa) fasta scores: E(): 2.9e-129, 67.53% id in 462 aa; Belongs to the class-II DAHP synthase family. (462 aa)    
Predicted Functional Partners:
DIP0834
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 11.8 kDa protein Rv0948c or MT0975 or MTCY10D7.26 SW:Y948_MYCTU (P71562) (105 aa) fasta scores: E(): 1.6e-14, 62.35% id in 85 aa.
   
 
 0.999
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
  
 0.979
DIP1617
Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
       0.676
DIP1618
Putative acyltransferase; Similar to Corynebacterium glutamicum hypothetical 27.1 kDa protein TR:Q9KKE6 (EMBL:AF096280) (245 aa) fasta scores: E(): 1.9e-67, 67.91% id in 240 aa, and to Streptomyces coelicolor putative acyltransferase 2SCG1.03 TR:Q9FCD9 (EMBL:AL391014) (240 aa) fasta scores: E(): 1.3e-37, 46.63% id in 238 aa.
       0.602
glk
Glucose kinase; Similar to Corynebacterium glutamicum glucose kinase Glk TR:Q9KKE7 (EMBL:AF096280) (323 aa) fasta scores: E(): 2.5e-79, 62.38% id in 319 aa, and to Streptomyces coelicolor glucokinase Glk or SC6E10.20c SW:GLK_STRCO (P40184) (317 aa) fasta scores: E(): 5.7e-45, 40% id in 310 aa.
       0.559
DIP1347
Similar to Mycobacterium leprae putative shikimate 5-dehydrogenase AroE or ML0515 SWALL:Q9CCS7 (EMBL:AL583918) (278 aa) fasta scores: E(): 5e-33, 45.42% id in 273 aa, and to Bacillus subtilis shikimate 5-dehydrogenase AroD SWALL:AROE_BACSU (SWALL:P54374) (280 aa) fasta scores: E(): 1.2e-13, 28.36% id in 282 aa.
 
   
 0.545
DIP1790
Glutamine amidotransferase protein; N-terminal region is similar to Streptomyces griseus para-aminobenzoate synthase Pab SW:PABS_STRGR (P32483) (723 aa) fasta scores: E(): 1.8e-48, 39.11% id in 698 aa, and to Streptomyces pristinaespiralis p-aminobenzoate synthase PapA TR:P72539 (EMBL:U60417) (719 aa) fasta scores: E(): 6.1e-43, 35.83% id in 734 aa.
  
  
 0.504
DIP1620
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 41.1 kDa protein ML0886 or MLCB268.31c TR:O69579 (EMBL:AL022602) (384 aa) fasta scores: E(): 1.9e-64, 51.18% id in 381 aa, and to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT2243 TR:AAK46529 (EMBL:AE007070) (385 aa) fasta scores: E(): 8e-64, 50.65% id in 381 aa.
       0.501
DIP1621
Similar to Mycobacterium leprae putative secreted protein ML0885 or MLCB268.32c TR:O69580 (EMBL:AL022602) (374 aa) fasta scores: E(): 1.7e-22, 36.2% id in 348 aa.
       0.495
DIP1622
Conserved hypothetical protein; Similar to the C-terminal region of Mycobacterium leprae putative secreted protein ML0885 or MLCB268.32c TR:O69580 (EMBL:AL022602) (374 aa) fasta scores: E(): 6e-19, 40.35% id in 223 aa.
       0.462
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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