STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mshDPutative acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. (303 aa)    
Predicted Functional Partners:
cysS2
cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
  
  
 0.955
mshB
Conserved hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
  
   
 0.948
mca
Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
   
 0.907
mshA
Putative glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
  
   
 0.897
DIP1797
Similar to Mycobacterium tuberculosis hypothetical protein Rv2466c TR:O53193 (EMBL:AL021246) (207 aa) fasta scores: E(): 2.5e-43, 57.63% id in 203 aa, and to Mycobacterium leprae hypothetical protein ML1485 TR:Q9CBY0 (EMBL:AL583922) (207 aa) fasta scores: E(): 1.7e-40, 55.94% id in 202 aa.
  
     0.771
pstC
Phosphate transport system permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
     
 0.729
DIP1912
Putative secreted protein; Poor database matches. Similar to Mycobacterium leprae probable exported protein ML2195 TR:Q50040 (EMBL:U15182) (283 aa) fasta scores: E(): 0.44, 23.39% id in 265 aa.
       0.695
DIP0653
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 14.5 kDa protein ML0284 or MLCB4.27c TR:O69598 (EMBL:AL023514) (137 aa) fasta scores: E(): 3.5e-22, 50% id in 140 aa.
  
     0.674
DIP1910
Putative phosphate-binding periplasmic protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
       0.594
DIP0823
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3292 TR:AAK47635 (EMBL:AE007142) (84 aa) fasta scores: E(): 4.4e-12, 48.1% id in 79 aa.
  
    0.591
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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