node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BP0104 | lipA | BP0104 | BP0106 | Similar to Neisseria meningitidis hypothetical protein Nma1380 or Nmb1218 TR:Q9JRI4 (EMBL:AL162755) (91 aa) fasta scores: E(): 4.4e-11, 46.988% id in 83 aa, and to Escherichia coli hypothetical protein YbeD or B0631 or Z0776 or ECS0669 SW:YBED_ECOLI (P30977) (87 aa) fasta scores: E(): 4.4e-06, 38.554% id in 83 aa; Belongs to the UPF0250 family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.727 |
BP0104 | lipB | BP0104 | BP0105 | Similar to Neisseria meningitidis hypothetical protein Nma1380 or Nmb1218 TR:Q9JRI4 (EMBL:AL162755) (91 aa) fasta scores: E(): 4.4e-11, 46.988% id in 83 aa, and to Escherichia coli hypothetical protein YbeD or B0631 or Z0776 or ECS0669 SW:YBED_ECOLI (P30977) (87 aa) fasta scores: E(): 4.4e-06, 38.554% id in 83 aa; Belongs to the UPF0250 family. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.918 |
BP0628 | BP1297 | BP0628 | BP1297 | Similar to Zea mays pyruvate dehydrogenase E1 beta subunit isoform 2 Pdh2 TR:Q9ZQY2 (EMBL:AF069909) (374 aa) fasta scores: E(): 4.3e-56, 47.077% id in 325 aa, and to Rhizobium loti acetoin dehydrogenase Mll3628 TR:Q98FT4 (EMBL:AP003002) (332 aa) fasta scores: E(): 3.5e-60, 51.713% id in 321 aa. | Similar to Pyrococcus abyssi lipoate-protein ligase A related Pab1916 TR:Q9V0V8 (EMBL:AJ248285) (249 aa) fasta scores: E(): 2e-24, 37.02% id in 235 aa, and to Pyrococcus horikoshii 249aa long hypothetical lipoate protein ligase Ph1487 TR:O59156 (EMBL:AP000006) (249 aa) fasta scores: E(): 5e-23, 34.89% id in 235 aa. | 0.784 |
BP0628 | gcvH | BP0628 | BP0196 | Similar to Zea mays pyruvate dehydrogenase E1 beta subunit isoform 2 Pdh2 TR:Q9ZQY2 (EMBL:AF069909) (374 aa) fasta scores: E(): 4.3e-56, 47.077% id in 325 aa, and to Rhizobium loti acetoin dehydrogenase Mll3628 TR:Q98FT4 (EMBL:AP003002) (332 aa) fasta scores: E(): 3.5e-60, 51.713% id in 321 aa. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.802 |
BP0628 | gcvP | BP0628 | BP0197 | Similar to Zea mays pyruvate dehydrogenase E1 beta subunit isoform 2 Pdh2 TR:Q9ZQY2 (EMBL:AF069909) (374 aa) fasta scores: E(): 4.3e-56, 47.077% id in 325 aa, and to Rhizobium loti acetoin dehydrogenase Mll3628 TR:Q98FT4 (EMBL:AP003002) (332 aa) fasta scores: E(): 3.5e-60, 51.713% id in 321 aa. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.415 |
BP0628 | lipA | BP0628 | BP0106 | Similar to Zea mays pyruvate dehydrogenase E1 beta subunit isoform 2 Pdh2 TR:Q9ZQY2 (EMBL:AF069909) (374 aa) fasta scores: E(): 4.3e-56, 47.077% id in 325 aa, and to Rhizobium loti acetoin dehydrogenase Mll3628 TR:Q98FT4 (EMBL:AP003002) (332 aa) fasta scores: E(): 3.5e-60, 51.713% id in 321 aa. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.535 |
BP0628 | lipB | BP0628 | BP0105 | Similar to Zea mays pyruvate dehydrogenase E1 beta subunit isoform 2 Pdh2 TR:Q9ZQY2 (EMBL:AF069909) (374 aa) fasta scores: E(): 4.3e-56, 47.077% id in 325 aa, and to Rhizobium loti acetoin dehydrogenase Mll3628 TR:Q98FT4 (EMBL:AP003002) (332 aa) fasta scores: E(): 3.5e-60, 51.713% id in 321 aa. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.500 |
BP0628 | lpdA | BP0628 | BP0618 | Similar to Zea mays pyruvate dehydrogenase E1 beta subunit isoform 2 Pdh2 TR:Q9ZQY2 (EMBL:AF069909) (374 aa) fasta scores: E(): 4.3e-56, 47.077% id in 325 aa, and to Rhizobium loti acetoin dehydrogenase Mll3628 TR:Q98FT4 (EMBL:AP003002) (332 aa) fasta scores: E(): 3.5e-60, 51.713% id in 321 aa. | Similar to Escherichia coli dihydrolipoamide dehydrogenase LpdA or Lpd or B0116 SW:DLDH_ECOLI (P00391) (473 aa) fasta scores: E(): 4.1e-94, 55.579% id in 466 aa, and to Salmonella enterica subspenterica serovar Typhimurium. dihydrolipoamide dehydrogenase Lpd TR:Q9ACP1 (EMBL:AJ297525) (475 aa) fasta scores: E(): 4.7e-94, 55.246% id in 467 aa. | 0.999 |
BP0628 | lpdA-2 | BP0628 | BP0995 | Similar to Zea mays pyruvate dehydrogenase E1 beta subunit isoform 2 Pdh2 TR:Q9ZQY2 (EMBL:AF069909) (374 aa) fasta scores: E(): 4.3e-56, 47.077% id in 325 aa, and to Rhizobium loti acetoin dehydrogenase Mll3628 TR:Q98FT4 (EMBL:AP003002) (332 aa) fasta scores: E(): 3.5e-60, 51.713% id in 321 aa. | Similar to Escherichia coli dihydrolipoamide dehydrogenase LpdA or Lpd or B0116 or Z0126 or ecs0120 SW:DLDH_ECOLI (P00391) (473 aa) fasta scores: E(): 7.8e-97, 63.713% id in 474 aa, and to Alcaligenes eutrophus dihydrolipoamide dehydrogenase PdhL TR:Q59099 (EMBL:U09865) (594 aa) fasta scores: E(): 4.8e-147, 75.541% id in 601 aa. | 0.999 |
BP0628 | pdhA | BP0628 | BP0629 | Similar to Zea mays pyruvate dehydrogenase E1 beta subunit isoform 2 Pdh2 TR:Q9ZQY2 (EMBL:AF069909) (374 aa) fasta scores: E(): 4.3e-56, 47.077% id in 325 aa, and to Rhizobium loti acetoin dehydrogenase Mll3628 TR:Q98FT4 (EMBL:AP003002) (332 aa) fasta scores: E(): 3.5e-60, 51.713% id in 321 aa. | Putative pyruvate dehydrogenase E1 component, alpha subunit; Similar to Clostridium magnum TPP-dependent acetoin dehydrogenase alpha-subunit TR:Q46142 (EMBL:L31844) (326 aa) fasta scores: E(): 8.2e-48, 43.631% id in 314 aa, and to Pseudomonas aeruginosa probable dehydrogenase e1 component Pa4150 TR:Q9HWN1 (EMBL:AE004831) (324 aa) fasta scores: E(): 3.1e-48, 45.541% id in 314 aa. | 0.999 |
BP1297 | BP0628 | BP1297 | BP0628 | Similar to Pyrococcus abyssi lipoate-protein ligase A related Pab1916 TR:Q9V0V8 (EMBL:AJ248285) (249 aa) fasta scores: E(): 2e-24, 37.02% id in 235 aa, and to Pyrococcus horikoshii 249aa long hypothetical lipoate protein ligase Ph1487 TR:O59156 (EMBL:AP000006) (249 aa) fasta scores: E(): 5e-23, 34.89% id in 235 aa. | Similar to Zea mays pyruvate dehydrogenase E1 beta subunit isoform 2 Pdh2 TR:Q9ZQY2 (EMBL:AF069909) (374 aa) fasta scores: E(): 4.3e-56, 47.077% id in 325 aa, and to Rhizobium loti acetoin dehydrogenase Mll3628 TR:Q98FT4 (EMBL:AP003002) (332 aa) fasta scores: E(): 3.5e-60, 51.713% id in 321 aa. | 0.784 |
BP1297 | gcvH | BP1297 | BP0196 | Similar to Pyrococcus abyssi lipoate-protein ligase A related Pab1916 TR:Q9V0V8 (EMBL:AJ248285) (249 aa) fasta scores: E(): 2e-24, 37.02% id in 235 aa, and to Pyrococcus horikoshii 249aa long hypothetical lipoate protein ligase Ph1487 TR:O59156 (EMBL:AP000006) (249 aa) fasta scores: E(): 5e-23, 34.89% id in 235 aa. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.940 |
BP1297 | lipA | BP1297 | BP0106 | Similar to Pyrococcus abyssi lipoate-protein ligase A related Pab1916 TR:Q9V0V8 (EMBL:AJ248285) (249 aa) fasta scores: E(): 2e-24, 37.02% id in 235 aa, and to Pyrococcus horikoshii 249aa long hypothetical lipoate protein ligase Ph1487 TR:O59156 (EMBL:AP000006) (249 aa) fasta scores: E(): 5e-23, 34.89% id in 235 aa. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.928 |
BP1297 | lipB | BP1297 | BP0105 | Similar to Pyrococcus abyssi lipoate-protein ligase A related Pab1916 TR:Q9V0V8 (EMBL:AJ248285) (249 aa) fasta scores: E(): 2e-24, 37.02% id in 235 aa, and to Pyrococcus horikoshii 249aa long hypothetical lipoate protein ligase Ph1487 TR:O59156 (EMBL:AP000006) (249 aa) fasta scores: E(): 5e-23, 34.89% id in 235 aa. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.922 |
BP1297 | lpdA | BP1297 | BP0618 | Similar to Pyrococcus abyssi lipoate-protein ligase A related Pab1916 TR:Q9V0V8 (EMBL:AJ248285) (249 aa) fasta scores: E(): 2e-24, 37.02% id in 235 aa, and to Pyrococcus horikoshii 249aa long hypothetical lipoate protein ligase Ph1487 TR:O59156 (EMBL:AP000006) (249 aa) fasta scores: E(): 5e-23, 34.89% id in 235 aa. | Similar to Escherichia coli dihydrolipoamide dehydrogenase LpdA or Lpd or B0116 SW:DLDH_ECOLI (P00391) (473 aa) fasta scores: E(): 4.1e-94, 55.579% id in 466 aa, and to Salmonella enterica subspenterica serovar Typhimurium. dihydrolipoamide dehydrogenase Lpd TR:Q9ACP1 (EMBL:AJ297525) (475 aa) fasta scores: E(): 4.7e-94, 55.246% id in 467 aa. | 0.939 |
BP1297 | lpdA-2 | BP1297 | BP0995 | Similar to Pyrococcus abyssi lipoate-protein ligase A related Pab1916 TR:Q9V0V8 (EMBL:AJ248285) (249 aa) fasta scores: E(): 2e-24, 37.02% id in 235 aa, and to Pyrococcus horikoshii 249aa long hypothetical lipoate protein ligase Ph1487 TR:O59156 (EMBL:AP000006) (249 aa) fasta scores: E(): 5e-23, 34.89% id in 235 aa. | Similar to Escherichia coli dihydrolipoamide dehydrogenase LpdA or Lpd or B0116 or Z0126 or ecs0120 SW:DLDH_ECOLI (P00391) (473 aa) fasta scores: E(): 7.8e-97, 63.713% id in 474 aa, and to Alcaligenes eutrophus dihydrolipoamide dehydrogenase PdhL TR:Q59099 (EMBL:U09865) (594 aa) fasta scores: E(): 4.8e-147, 75.541% id in 601 aa. | 0.937 |
BP1297 | pdhA | BP1297 | BP0629 | Similar to Pyrococcus abyssi lipoate-protein ligase A related Pab1916 TR:Q9V0V8 (EMBL:AJ248285) (249 aa) fasta scores: E(): 2e-24, 37.02% id in 235 aa, and to Pyrococcus horikoshii 249aa long hypothetical lipoate protein ligase Ph1487 TR:O59156 (EMBL:AP000006) (249 aa) fasta scores: E(): 5e-23, 34.89% id in 235 aa. | Putative pyruvate dehydrogenase E1 component, alpha subunit; Similar to Clostridium magnum TPP-dependent acetoin dehydrogenase alpha-subunit TR:Q46142 (EMBL:L31844) (326 aa) fasta scores: E(): 8.2e-48, 43.631% id in 314 aa, and to Pseudomonas aeruginosa probable dehydrogenase e1 component Pa4150 TR:Q9HWN1 (EMBL:AE004831) (324 aa) fasta scores: E(): 3.1e-48, 45.541% id in 314 aa. | 0.691 |
gcvH | BP0628 | BP0196 | BP0628 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Similar to Zea mays pyruvate dehydrogenase E1 beta subunit isoform 2 Pdh2 TR:Q9ZQY2 (EMBL:AF069909) (374 aa) fasta scores: E(): 4.3e-56, 47.077% id in 325 aa, and to Rhizobium loti acetoin dehydrogenase Mll3628 TR:Q98FT4 (EMBL:AP003002) (332 aa) fasta scores: E(): 3.5e-60, 51.713% id in 321 aa. | 0.802 |
gcvH | BP1297 | BP0196 | BP1297 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Similar to Pyrococcus abyssi lipoate-protein ligase A related Pab1916 TR:Q9V0V8 (EMBL:AJ248285) (249 aa) fasta scores: E(): 2e-24, 37.02% id in 235 aa, and to Pyrococcus horikoshii 249aa long hypothetical lipoate protein ligase Ph1487 TR:O59156 (EMBL:AP000006) (249 aa) fasta scores: E(): 5e-23, 34.89% id in 235 aa. | 0.940 |
gcvH | gcvP | BP0196 | BP0197 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |