STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (187 aa)    
Predicted Functional Partners:
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 
 0.925
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.923
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.923
BP0184
Putative exported protein; Similar to Neisseria meningitidis putative periplasmic protein Nma0295 TR:Q9JWM6 (EMBL:AL162752) (1371 aa) fasta scores: E(): 1.4e-18, 23.644% id in 1383 aa, and to Pseudomonas aeruginosa hypothetical protein Pa2542 TR:Q9I0U2 (EMBL:AE004682) (1221 aa) fasta scores: E(): 7.2e-14, 27.344% id in 1280 aa.
       0.727
BP0183
Putative exported protein; Similar to Xanthomonas oryzae pvoryzae putative outer membrane protein TR:Q9EY32 (EMBL:AY010120) (593 aa) fasta scores: E(): 8.2e-16, 24.540% id in 652 aa, and to Pseudomonas aeruginosa hypothetical protein Pa2543 TR:Q9I0U1 (EMBL:AE004682) (579 aa) fasta scores: E(): 9.1e-13, 24.342% id in 608 aa.
       0.702
BP0182
Putative iron sulfur binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
      0.652
cyaA
Bifunctional hemolysin-adenylate cyclase precursor; This adenylate cyclase belongs to a special class of bacterial toxin. It causes whooping cough by acting on mammalian cells by elevating cAMP-concentration and thus disrupts normal cell function; In the C-terminal section; belongs to the RTX prokaryotic toxin family.
   
  
 0.650
rfbD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
   
    0.598
omlA
Outer membrane lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
    0.530
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
  
 0.512
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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