STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
rocDOrnithine aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (413 aa)    
Predicted Functional Partners:
BP0538
Arginase; Similar to Bacillus caldovelox arginase RocF SW:ARGI_BACCD (P53608) (299 aa) fasta scores: E(): 3.5e-44, 44.000% id in 300 aa, and to Rhizobium loti arginase Mll6778 TR:Q988E1 (EMBL:AP003010) (310 aa) fasta scores: E(): 3.2e-44, 45.847% id in 301 aa; Belongs to the arginase family.
 0.993
BP0429
Similar to Homo sapiens delta-1-pyrroline-5-carboxylate dehydrogenase precursor AldH4a1 or P5cdh or AldH4 SW:PUT2_HUMAN (P30038) (563 aa) fasta scores: E(): 7.8e-101, 50.094% id in 531 aa, and to Mycobacterium tuberculosis delta-1-pyrroline-5-carboxylate dehydrogenase RocA or Rv1187 or Mtv005.23 TR:O50443 (EMBL:AL010186) (543 aa) fasta scores: E(): 1.7e-118, 58.868% id in 530 aa.
 
 0.945
putA
Bifunctional proline oxidoreductase/transcriptional repressor; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.926
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
   
 0.921
BP0354
Similar to Halobacterium sp ornithine cyclodeaminase Ocd2 or Vng1364G TR:Q9HQ24 (EMBL:AE005056) (328 aa) fasta scores: E(): 3.7e-18, 31.494% id in 308 aa, and to Rhizobium loti ornithine cyclodeaminase Ocd2 or Mlr3204 TR:Q98GR8 (EMBL:AP003001) (321 aa) fasta scores: E(): 5.4e-16, 33.127% id in 323 aa.
  
 
 0.905
osmC
Osmotically inducible protein C (Pseudogene); (G)4 in pertussis; (G)2 in parapertussis and bronchiseptica.
  
 
 0.905
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 0.885
argA
Similar to Pseudomonas aeruginosa amino-acid acetyltransferase ArgA or pa5204 SW:ARGA_PSEAE (P22567) (432 aa) fasta scores: E(): 2.8e-71, 45.7% id in 431 aa, and to Escherichia coli amino-acid acetyltransferase ArgA or b2818 or z4135 or ecs3675 SW:ARGA_ECOLI (P08205) (443 aa) fasta scores: E(): 9.1e-71, 42.06% id in 435 aa; Belongs to the acetyltransferase family. ArgA subfamily.
  
  
 0.831
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.762
argJ
Arginine biosynthesis bifunctional protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
  
 0.759
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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