STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BP0662Probable enoyl-CoA hydratase; Similar to Clostridium acetobutylicum 3-hydroxybutyryl-CoA dehydratase Crt or Cac2712 SW:CRT_CLOAB (P52046) (261 aa) fasta scores: E(): 8.8e-24, 33.725% id in 255 aa, and to Halobacterium sp enoyl-CoA hydratase Fad2 or Vng0428G TR:Q9HS32 (EMBL:AE004998) (256 aa) fasta scores: E(): 8.7e-24, 35.878% id in 262 aa. (259 aa)    
Predicted Functional Partners:
BP0661
Similar to Entamoeba histolytica acetyl-CoA synthetase TR:Q9NAT4 (EMBL:AF286346) (713 aa) fasta scores: E(): 7.1e-57, 32.460% id in 687 aa, and to Pseudomonas aeruginosa pimeloyl-CoA synthetase pa1017 TR:Q9I4V6 (EMBL:AE004534) (715 aa) fasta scores: E(): 5.4e-63, 32.345% id in 708 aa.
  
    0.822
bvgS
Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.
    
 
 0.807
BP0217
Similar to Clostridium acetobutylicum 3-hydroxybutyryl-CoA dehydrogenase Hbd or Cac2708 SW:HBD_CLOAB (P52041) (282 aa) fasta scores: E(): 7.6e-33, 42.199% id in 282 aa, and to Rhizobium loti 3-hydroxybutyryl-CoA dehydrogenase Mlr6793 TR:Q988C8 (EMBL:AP003010) (309 aa) fasta scores: E(): 3.7e-37, 36.452% id in 310 aa.
 
 0.786
BP2059
Putative thiolase; Similar to many thioloases e.g. Alcaligenes eutrophus beta-ketothiolase bktB TR:O68275 (EMBL:AF026544) (394 aa) fasta scores: E(): 3.1e-106, 75.897% id in 390 aa and Clostridium acetobutylicum acetyl-CoA acetyltransferase thl or CAC2873 SW:THL_CLOAB (P45359) (392 aa) fasta scores: E(): 8.6e-70, 52.051% id in 390 aa; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.648
BP0422
Probable thiolase; Similar to Alcaligenes eutrophus acetyl-CoA acetyltransferase PhbA SW:THIL_ALCEU (P14611) (393 aa) fasta scores: E(): 1.5e-60, 46.530% id in 389 aa, and to Rhizobium meliloti probable thiolase Sma1450 TR:AAK65449 (EMBL:AE007266) (396 aa) fasta scores: E(): 7e-83, 60.870% id in 391 aa. Also similar to BP0447 (53.684% identity in 380 aa overlap); Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.628
BP0668
Probable thiolase; Similar to Cucurbita maxima 3-ketoacyl-CoA thiolase precursor TR:P93112 (EMBL:D70895) (461 aa) fasta scores: E(): 1.1e-50, 42.569% id in 397 aa, and to Deinococcus radiodurans acetyl-CoA acetyltransferase Dr1428 TR:Q9RUF8 (EMBL:AE001987) (402 aa) fasta scores: E(): 4.6e-94, 65.140% id in 393 aa; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.628
BP1784
Putative thiolase; Similar to Pseudomonas aeruginosa hypothetical protein Pa1016 TR:Q9I4V7 (EMBL:AE004534) (383 aa) fasta scores: E(): 7.5e-88, 60.31% id in 378 aa, and to Methanothermobacter thermautotrophicus lipid-transfer protein Mth793 TR:O26884 (EMBL:AE000857) (383 aa) fasta scores: E(): 8e-31, 32.03% id in 384 aa.
  
 0.628
BP2099
Similar to many putative thiolases e.g. Caulobacter crescentus thiolase family protein CC1432 TR:Q9A8C2 (EMBL:AE005818) (400 aa) fasta scores: E(): 1.5e-111, 67.929% id in 396 aa; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.628
BP0026
Putative thiolase; Similar to Mycobacterium tuberculosis CDC1551 nonspecific lipid-transfer protein mt1663 TR:AAK45933 (EMBL:AE007030) (402 aa) fasta scores: E(): 5.1e-14, 27.229% id in 415 aa, and to Pseudomonas fluorescens PhlC TR:Q51727 (EMBL:U41818) (398 aa) fasta scores: E(): 5.2e-15, 27.188% id in 320 aa.
  
 0.598
BP0636
Conserved hypothetical protein; Similar to Rhodococcus spNCIMB 9784 non-specific lipid carrier-like protein CampC TR:AAK50624 (EMBL:AF323755) (408 aa) fasta scores: E(): 8.1e-37, 35.106% id in 376 aa, and to Pseudomonas aeruginosa hypothetical protein Pa1016 TR:Q9I4V7 (EMBL:AE004534) (383 aa) fasta scores: E(): 2.1e-46, 41.425% id in 379 aa.
  
 0.545
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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