STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bfrDProbable TonB-dependent receptor for iron transport; Probably involved in iron transport; Belongs to the TonB-dependent receptor family. (743 aa)    
Predicted Functional Partners:
sphB1
Previously sequenced as Bordetella pertussis autotransporter subtilisin-like protease SphB1 TR:CAC44081 (EMBL:AJ318229) (1039 aa) fasta scores: E(): 0, 100.000% id in 932 aa, and dimilar to Xylella fastidiosa serine protease Xf1026 TR:Q9PEK2 (EMBL:AE003939) (905 aa) fasta scores: E(): 1.1e-45, 31.919% id in 943 aa.
   
  
 0.957
tcfA
Tracheal colonization factor precursor; Identical to the previously sequenced Bordetella pertussis tracheal colonization factor precursor Tcfa2 TR:O86135 (EMBL:AJ009785) (647 aa) fasta scores: E(): 1.7e-171, 99.84% id in 647 aa.
   
  
 0.955
ompQ
Outer membrane porin protein OmpQ; Previously described as Bordetella pertussis OmpQ TR:Q45342 (EMBL:U16266) (364 aa) fasta scores: E(): 1.5e-148, 99.72% id in 364 aa. Similar to Bordetella pertussis outer membrane porin protein precursor SW:OMP_BORPE (Q04064) (385 aa) fasta scores: E(): 2.4e-13, 34.25% id in 400 aa, and to Neisseria meningitidis major outer membrane protein Porb or nma0398 SW:OMB_NEIMA (P57042) (329 aa) fasta scores: E(): 7e-05, 24.5% id in 351 aa.
   
    0.955
brkA
Serum resistance protein; Inhibits the classical pathway of complement activation and prevents accumulation of deposited C4.
   
  
 0.953
BP2925
Similar to Rhizobium meliloti hypothetical protein Smb20529 TR:CAC48908 (EMBL:AL603643) (309 aa) fasta scores: E(): 3.9e-53, 52.76% id in 271 aa and to Caulobacter crescentus hypothetical protein Cc3255 TR:Q9A3E9 (EMBL:AE005989) (280 aa) fasta scores: E(): 1.2e-44, 48.14% id in 270 aa; Belongs to the UPF0276 family.
   
    0.936
ptxB
Pertussis toxin subunit 2 precursor; PTX oligomer B binds to receptors on the eukaryotic cell surface and facilitates the translocation of the toxic subunit across the cell membrane.
   
    0.929
ptxE
Pertussis toxin subunit 5 precursor; PTX oligomer B binds to receptors on the eukaryotic cell surface and facilitates the translocation of the toxic subunit across the cell membrane.
   
    0.926
ptxD
Pertussis toxin subunit 4 precursor; PTX oligomer B binds to receptors on the eukaryotic cell surface and facilitates the translocation of the toxic subunit across the cell membrane.
   
    0.924
ptxC
Pertussis toxin subunit 3 precursor; PTX oligomer B binds to receptors on the eukaryotic cell surface and facilitates the translocation of the toxic subunit across the cell membrane.
   
    0.915
ptlB
Pertussis toxin transport protein; Component of the type IV secretion system ptl required for secretion of assembled pertussis toxin (PTX) through the outer membrane.
   
    0.913
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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