STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BP2067Putative superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (170 aa)    
Predicted Functional Partners:
BP2860
Probable cation-transporting ATPase; Highly similar to Rhizobium meliloti copper-transporting ATPase ActP SW:ATCU_RHIME (Q9X5X3) (827 aa) fasta scores: E(): 1.5e-179, 66.58% id in 802 aa, and to Synechococcus sp cation-transporting ATPase PacS SW:ATCS_SYNP7 (P37279) (747 aa) fasta scores: E(): 2.3e-110, 49.33% id in 748 aa. Note the differing predicted N-termini of these proteins. The Bordetella protein is predicted to be ~18 aa shorter than the other two examples. The upstream IS481 element may offer one explanation for this. It is also not clear if the insertion of this IS element af [...]
  
 0.976
BP1727
Putative exported protein; Similar to Pseudomonas syringae OrfH protein TR:Q9KWM7 (EMBL:AB033420) (65 aa) fasta scores: E(): 2.9e-05, 43.54% id in 62 aa, and to Agrobacterium tumefaciens strC58 Agr_c_2220p TR:AAK87005 (EMBL:AE008049) (84 aa) fasta scores: E(): 2.5e-07, 47.61% id in 63 aa.
   
 0.936
petB
Cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
 
 0.846
katA
Catalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
  
 0.793
sodB
Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.792
ilvD-2
Similar to Lactococcus lactis dihydroxy-acid dehydratase IlvD SW:ILVD_LACLA (Q02139) (570 aa) fasta scores: E(): 5.1e-94, 47.13% id in 558 aa, and to Bacillus subtilis dihydroxy-acid dehydratase IlvD SW:ILVD_BACSU (P51785) (557 aa) fasta scores: E(): 7.9e-87, 43.08% id in 557 aa. Also similar to BP0289, 36.661% identity (40.653% ungapped) in 611 aa overlap; Belongs to the IlvD/Edd family.
   
    0.785
petA
Ubiquinol-cytochrome C reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
 
 0.778
BP0562
Putative exported protein; Similar to Rhizobium loti Mll3326 protein TR:Q98GH4 (EMBL:AP003001) (179 aa) fasta scores: E(): 6.4e-18, 41.830% id in 153 aa, and to Neisseria meningitidis hypothetical protein Nmb1557 TR:Q9JYJ5 (EMBL:AE002506) (157 aa) fasta scores: E(): 1e-15, 40.541% id in 148 aa.
    
   0.767
BP2953
Conserved hypothetical protein; Similar to Thauera aromatica ypothetical protein BbsI TR:Q9KJE6 (EMBL:AF173961) (209 aa) fasta scores: E(): 2.9e-49, 58.04% id in 205 aa and to Xylella fastidiosa hypothetical protein Xf2170 TR:Q9PBH4 (EMBL:AE004031) (204 aa) fasta scores: E(): 7.3e-40, 50.24% id in 205 aa.
   
   0.763
BP1301
Glutathione peroxidase; Similar to Schizosaccharomyces pombe glutathione peroxidase Gpx1 or Spbc32f12.03C SW:GSHJ_SCHPO (O59858) (158 aa) fasta scores: E(): 1.7e-32, 50.96% id in 155 aa, and to Pseudomonas aeruginosa glutathione peroxidase Pa2826 TR:Q9I017 (EMBL:AE004709) (161 aa) fasta scores: E(): 1.3e-39, 61.68% id in 154 aa.
   
 0.751
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.