node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BP2197 | bamB | BP2197 | BP2196 | Putative membrane protein; Similar to Neisseria meningitidis putative membrane protein NMA1064 TR:Q9JV00 (EMBL:AL162755) (209 aa) fasta scores: E(): 4.8e-16, 35.07% id in 211 aa. | Putative quinoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.975 |
BP2197 | der | BP2197 | BP2195 | Putative membrane protein; Similar to Neisseria meningitidis putative membrane protein NMA1064 TR:Q9JV00 (EMBL:AL162755) (209 aa) fasta scores: E(): 4.8e-16, 35.07% id in 211 aa. | Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.880 |
BP2197 | hisS | BP2197 | BP2198 | Putative membrane protein; Similar to Neisseria meningitidis putative membrane protein NMA1064 TR:Q9JV00 (EMBL:AL162755) (209 aa) fasta scores: E(): 4.8e-16, 35.07% id in 211 aa. | Similar to Escherichia coli and histidyl-tRNA synthetase HisS or b2514 or z3777 or ecs3376 SW:SYH_ECOLI (P04804) (423 aa) fasta scores: E(): 3.1e-88, 55.89% id in 424 aa. | 0.961 |
BP2197 | ispG | BP2197 | BP2199 | Putative membrane protein; Similar to Neisseria meningitidis putative membrane protein NMA1064 TR:Q9JV00 (EMBL:AL162755) (209 aa) fasta scores: E(): 4.8e-16, 35.07% id in 211 aa. | 1-hydroxy-2-methyl-2-(E)-butenyl4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.819 |
BP2197 | ndk | BP2197 | BP2202 | Putative membrane protein; Similar to Neisseria meningitidis putative membrane protein NMA1064 TR:Q9JV00 (EMBL:AL162755) (209 aa) fasta scores: E(): 4.8e-16, 35.07% id in 211 aa. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.729 |
BP2197 | rlmN | BP2197 | BP2201 | Putative membrane protein; Similar to Neisseria meningitidis putative membrane protein NMA1064 TR:Q9JV00 (EMBL:AL162755) (209 aa) fasta scores: E(): 4.8e-16, 35.07% id in 211 aa. | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.793 |
BP2197 | valS | BP2197 | BP2203 | Putative membrane protein; Similar to Neisseria meningitidis putative membrane protein NMA1064 TR:Q9JV00 (EMBL:AL162755) (209 aa) fasta scores: E(): 4.8e-16, 35.07% id in 211 aa. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.520 |
alaS | aspS | BP1836 | BP0709 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.796 |
alaS | der | BP1836 | BP2195 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.583 |
alaS | hisS | BP1836 | BP2198 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Similar to Escherichia coli and histidyl-tRNA synthetase HisS or b2514 or z3777 or ecs3376 SW:SYH_ECOLI (P04804) (423 aa) fasta scores: E(): 3.1e-88, 55.89% id in 424 aa. | 0.797 |
alaS | valS | BP1836 | BP2203 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.861 |
aspS | alaS | BP0709 | BP1836 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.796 |
aspS | hisS | BP0709 | BP2198 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Similar to Escherichia coli and histidyl-tRNA synthetase HisS or b2514 or z3777 or ecs3376 SW:SYH_ECOLI (P04804) (423 aa) fasta scores: E(): 3.1e-88, 55.89% id in 424 aa. | 0.941 |
aspS | valS | BP0709 | BP2203 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.825 |
bamB | BP2197 | BP2196 | BP2197 | Putative quinoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative membrane protein; Similar to Neisseria meningitidis putative membrane protein NMA1064 TR:Q9JV00 (EMBL:AL162755) (209 aa) fasta scores: E(): 4.8e-16, 35.07% id in 211 aa. | 0.975 |
bamB | der | BP2196 | BP2195 | Putative quinoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.881 |
bamB | hisS | BP2196 | BP2198 | Putative quinoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Similar to Escherichia coli and histidyl-tRNA synthetase HisS or b2514 or z3777 or ecs3376 SW:SYH_ECOLI (P04804) (423 aa) fasta scores: E(): 3.1e-88, 55.89% id in 424 aa. | 0.913 |
bamB | ispG | BP2196 | BP2199 | Putative quinoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 1-hydroxy-2-methyl-2-(E)-butenyl4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.793 |
bamB | ndk | BP2196 | BP2202 | Putative quinoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.723 |
bamB | rlmN | BP2196 | BP2201 | Putative quinoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.787 |