STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fhpFlavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. (402 aa)    
Predicted Functional Partners:
BP2211
Putative conserved DNA-binding protein; Similar to Escherichia coli, hypothetical protein YjeB or b4178 or z5785 or ecs5154 SW:YJEB_ECOLI (P21498) (141 aa) fasta scores: E(): 3.1e-18, 44.61% id in 130 aa.
 
  
 0.925
aroG
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (pseudogene); (GAGG)2 in pertussis; (GAGG)1 in parapertussis and bronchiseptica.
      0.914
BP2108
Putative membrane protein; Similar to hypothetical proteins e.g. Pseudomonas aeruginosa hypothetical protein PA2662 TR:Q9I0H6 (EMBL:AE004695) (397 aa) fasta scores: E(): 7.8e-34, 39.747% id in 395 aa.
  
  
 0.799
BP1652
Putative oxidoreductase (Partial); Partial CDS, it lacks the N-terminal region. Similar to Pseudomonas putida putidaredoxin reductase camA SW:CAMA_PSEPU (P16640) (422 aa) fasta scores: E(): 5.1e-34, 40.98% id in 283 aa, and to Rhizobium meliloti putative oxidoreductase protein smc00914 TR:CAC45363 (EMBL:AL591785) (405 aa) fasta scores: E(): 6.1e-47, 50.5% id in 299 aa.
  
  
 0.781
BP1579
Putative cytochrome C; Similar to Pseudomonas aeruginosa hypothetical protein Pa2481 TR:Q9I101 (EMBL:AE004676) (291 aa) fasta scores: E(): 2.4e-61, 58.8% id in 284 aa, and to Wolinella succinogenes CytA protein precursor cytA TR:CAC50081 (EMBL:AJ318778) (371 aa) fasta scores: E(): 5e-16, 36.14% id in 285 aa.
   
  
 0.573
BP2350
Globin-like protein; Similar to Burkholderia pseudomallei putative globin TR:AAK38159 (EMBL:AY030274) (170 aa) fasta scores: E(): 7.6e-35, 60% id in 140 aa, and to Mycobacterium tuberculosis, and hemoglobin-like protein Hbo GlbO or Rv2470 or Mt2546 or Mtv008.26 TR:AAK46846 (EMBL:AL021246) (134 aa) fasta scores: E(): 3.3e-09, 41.34% id in 104 aa.
 
  
 0.572
BP2405
Putative cytochrome p450 oxidoreductase; Similar to Streptomyces galilaeus AknT TR:Q9L4U5 (EMBL:AF264025) (443 aa) fasta scores: E(): 0.0076, 28.02% id in 389 aa, and to Rhodococcus fascians cytochrome p450 Fas1 or cyp105e1 SW:FAS1_RHOFA (P46373) (399 aa) fasta scores: E(): 0.48, 23.63% id in 402 aa.
     
 0.536
BP2213
Similar to Vibrio cholerae hypothetical protein Vc0519 TR:Q9KUK0 (EMBL:AE004138) (147 aa) fasta scores: E(): 2.4e-18, 51.04% id in 143 aa, and to Neisseria meningitidis hypothetical protein NMB1951 TR:Q9JXP0 (EMBL:AE002543) (180 aa) fasta scores: E(): 9.2e-18, 47.02% id in 168 aa.
       0.532
BP0785
Putative mechanosensitive channel protein; Similar to Rhizobium loti probable integral membrane protein Mlr0973 TR:Q98LL9 (EMBL:AP002996) (410 aa) fasta scores: E(): 1.5e-13, 28.019% id in 207 aa, and to Rhizobium meliloti conserved hypothetical membrane protein Smb20863 TR:CAC49557 (EMBL:AL603646) (343 aa) fasta scores: E(): 6.1e-13, 26.054% id in 261 aa.
  
  
 0.517
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
       0.511
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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