STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BP2268Similar to Escherichia coli methyl-accepting chemotaxis protein ii tar or chem or b1886 SW:MCP2_ECOLI (P07017) (553 aa) fasta scores: E(): 2.1e-60, 46.69% id in 484 aa. (513 aa)    
Predicted Functional Partners:
cheA
Chemotaxis protein CheY (Pseudogene); HMMPfam hit to PF00072, Response regulator receiver domain.
 
 0.995
cheW
Similar to Escherichia coli chemotaxis protein CheW or B1887 or Z2941 or Ecs2597 SW:CHEW_ECOLI (P07365) (167 aa) fasta scores: E(): 1.3e-41, 74.83% id in 155 aa, and to Burkholderia pseudomallei (Pseudomonas pseudomallei) chemotaxis protein CheW TR:O05183 (EMBL:U92493) (175 aa) fasta scores: E(): 7e-43, 72.56% id in 164 aa.
 
 0.995
cheB
Chemotaxis protein methyltransferase (Pseudogene); Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.985
cheD
Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
 0.980
cheY
Similar to Escherichia coli chemotaxis protein CheY or B1882 or Z2936 or Ecs2592 TR:AAG56872 (EMBL:K02175) (129 aa) fasta scores: E(): 5.1e-36, 78.73% id in 127 aa, and to Burkholderia pseudomallei (Pseudomonas pseudomallei) CheY TR:P94342 (EMBL:U78087) (131 aa) fasta scores: E(): 1.9e-37, 80.31% id in 127 aa.
 
 0.948
bvgS
Virulence sensor protein; Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals.
  
 
 0.761
BP0314
Similar to Vibrio cholerae hypothetical protein Vca1085 TR:Q9KKL8 (EMBL:AE004434) (556 aa) fasta scores: E(): 3.5e-23, 27.632% id in 456 aa, and to Thermotoga maritima conserved hypothetical protein Tm0735 TR:Q9WZJ4 (EMBL:AE001744) (455 aa) fasta scores: E(): 2.1e-13, 30.947% id in 475 aa.
 
    0.605
BP1990
Putative membrane protein; N-terminus is similar to the N-terminal region of similar to Pseudomonas aeruginosa hypothetical protein PaA1727 TR:Q9I310 (EMBL:AE004599) (685 aa) fasta scores: E(): 1.5e-17, 38.62% id in 189 aa. Similar to N-terminal region of Pseudomonas carboxydovorans hypothetical protein CoxC TR:Q9KX27 (EMBL:X82447) (402 aa) fasta scores: E(): 6.7e-16, 33.33% id in 264 aa.
 
  
 0.558
BP1992
Putative membrane protein; Similar to Bacillus halodurans late competence protein required for processing and translocation BH3035 TR:Q9K8H1 (EMBL:AP001517) (162 aa) fasta scores: E(): 0.0035, 26.41% id in 159 aa, and to the C-terminal region of Aeromonas hydrophila type 4 prepilin-like proteins leader peptide processing enzyme [includes: leader peptidase; N-methyltransferase] TapD SW:LEP4_AERHY (P45794) (290 aa) fasta scores: E(): 0.45, 27.84% id in 176 aa.
   
    0.541
BP1995
Putative membrane protein; N-terminus is similar to the N-terminal region of Pseudomonas aeruginosa hypothetical protein PA4305 TR:Q9HW95 (EMBL:AE004846) (303 aa) fasta scores: E(): 3.9e-14, 36.36% id in 242 aa, and Rhizobium meliloti putative pilus assembly signal peptide protein TR:CAC41527 (EMBL:AL591782) (269 aa) fasta scores: E(): 0.0098, 33.2% id in 250 aa.
   
    0.540
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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