STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)    
Predicted Functional Partners:
pykA
Pyruvate kinase; Similar to Escherichia coli pyruvate kinase II PykA or b1854 SW:KPY2_ECOLI (P21599) (479 aa) fasta scores: E(): 2.1e-96, 59.32% id in 477 aa.
  
 0.993
pgk
Similar to Escherichia coli phosphoglycerate kinase Pgk or B2926 SW:PGK_ECOLI (P11665) (386 aa) fasta scores: E(): 6.3e-83, 64.042% id in 381 aa, and to Alcaligenes eutrophus phosphoglycerate kinase, chromosomal CbbkC SW:PGKC_ALCEU (P50319) (413 aa) fasta scores: E(): 1.8e-103, 75.381% id in 394 aa.
 
 
 0.992
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.987
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 0.983
gap
Similar to Pseudomonas aeruginosa glyceraldehyde 3-phosphate dehydrogenase Gap or HexC or pa3195 SWALL:G3P_PSEAE (SWALL:P27726) (334 aa) fasta scores: E(): 9.1e-84, 66.07% id in 336 aa, and to Alcaligenes eutrophus glyceraldehyde 3-phosphate dehydrogenase, plasmid cbbgP SWALL:G3PP_ALCEU (SWALL:P50322) (336 aa) fasta scores: E(): 1.1e-107, 84.52% id in 336 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.981
gpmA
Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
  
 0.979
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.962
tktA
Transketolase 1; Similar to Escherichia coli transketolase 1 TktA or Tkt or B2935 SW:TKT1_ECOLI (P27302) (663 aa) fasta scores: E(): 5.7e-137, 63.433% id in 670 aa, and to Pasteurella multocida transketolase 1 TktA or Pm1242 SW:TKT1_PASMU (P57927) (668 aa) fasta scores: E(): 3e-158, 61.504% id in 678 aa; Belongs to the transketolase family.
  
 0.959
pgi
Similar to Zymomonas mobilis glucose-6-phosphate isomerase Pgi SW:G6PI_ZYMMO (P28718) (507 aa) fasta scores: E(): 6.4e-34, 31.46% id in 464 aa, and to Xanthomonas campestris glucose-6-phosphate isomerase Pgi TR:O68824 (EMBL:AF054807) (562 aa) fasta scores: E(): 1.4e-32, 31.1% id in 524 aa. Also similar to BP3142, 40.891% identity (43.238% ungapped) in 516 aa overlap.
  
 0.956
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 8.3e-106, 44.45% id in 1597 aa, and to Deinococcus radiodurans glutamate synthase, large subunit DR0183 TR:Q9RXX2 (EMBL:AE001880) (1615 aa) fasta scores: E(): 0, 70.42% id in 1579 aa.
  
  
 0.955
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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