STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (256 aa)    
Predicted Functional Partners:
era
GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
  
 0.960
rpsI
Similar to Escherichia coli 30s ribosomal protein S9 RpsI or b3230 or z4588 or Ecs4103 SW:RS9_ECOLI (P02363) (129 aa) fasta scores: E(): 3.5e-30, 65.35% id in 127 aa and to Neisseria meningitidis (serogroup A) 30s ribosomal protein S9 RpsI or Nma0379 or Nmb2056 TR:Q9JQZ9 (EMBL:AL162753) (130 aa) fasta scores: E(): 8.7e-38, 80.76% id in 130 aa; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.959
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
 
 
 0.957
rplM
50s ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.956
rpmA
Similar to Escherichia coli 50S ribosomal protein L27 RpmA or B3185 SW:RL27_ECOLI (P02427) (84 aa) fasta scores: E(): 2.8e-21, 71.084% id in 83 aa, and to Vibrio cholerae ribosomal protein L27 Vc0436 TR:Q9KUS9 (EMBL:AE004131) (86 aa) fasta scores: E(): 5.1e-23, 73.256% id in 86 aa; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.954
lep
Signal peptidase I; Previously sequenced Bordetella pertussis leader peptidase Lep TR:Q9RN42 (EMBL:AF188620) (294 aa) fasta scores: E(): 1.9e-121, 100% id in 294 aa. Highly similar to Escherichia coli signal peptidase I LepB or b2568 SW:LEP_ECOLI (P00803) (324 aa) fasta scores: E(): 3.7e-22, 41.81% id in 342 aa, and to; Belongs to the peptidase S26 family.
 
  
 0.951
rpmF
Similar to Neisseria meningitidis 50s ribosomal protein l32 RpmF or Nma0544 SW:RL32_NEIMA (Q9JW52) (58 aa) fasta scores: E(): 1e-15, 70.69% id in 58 aa and Pseudomonas aeruginosa 50s ribosomal protein l32 RpmF or Pa2970 SW:RL32_PSEAE (Q9HZN4) (59 aa) fasta scores: E(): 2.1e-13, 64.4% id in 59 aa; Belongs to the bacterial ribosomal protein bL32 family.
  
   0.951
rpsF
30s ribosomal protein s6; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.949
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
 
 0.948
rpsB
Similar to Escherichia coli 30S ribosomal protein S2 RpsB or B0169 or Z0180 or Ecs0171 SW:RS2_ECOLI (P02351) (240 aa) fasta scores: E(): 5.1e-52, 61.3% id in 230 aa, and to Spirulina platensis 30S ribosomal protein S2 RpsB SW:RS2_SPIPL (P34831) (251 aa) fasta scores: E(): 2.9e-57, 62.14% id in 243 aa; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.943
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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