STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppnKProbable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (299 aa)    
Predicted Functional Partners:
pntaA
Similar to Rhodospirillum rubrum NAD(P) transhydrogenase, alpha subunit part 1 PntaA or NntA1 SWALL:Q60164 (EMBL:U05294) (384 aa) fasta scores: E(): 8.2e-59, 51.32% id in 378 aa, and to Ralstonia solanacearum probable NAD(P) transhydrogenase PntaA or Rsc2730 or Rs00124 SWALL:CAD16437 (EMBL:AL646071) (379 aa) fasta scores: E(): 2.6e-96, 73.51% id in 370 aa.
     
 0.971
nadE
Putative NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.952
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.943
nudC
Similar to Escherichia coli NADH pyrophosphatase NudC SW:NUDC_ECOLI (P32664) (257 aa) fasta scores: E(): 2.8e-27, 46.98% id in 166 aa. Similar to Pasteurella multocida NADH pyrophosphatase PM1735 SW:NUDC_PASMU (P57965) (264 aa) fasta scores: E(): 5e-31, 39.18% id in 245 aa.
   
 
 0.905
BP2506
DNA repair protein; May be involved in recombinational repair of damaged DNA.
 
  
 0.889
pncB
Pututative nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
  
  
 0.749
surE
Stationary-phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
 
 0.684
dxs
1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
    
 0.651
nadX1
Conserved hypothetical protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
      
 0.641
nadX2
Putative exported protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
      
 0.641
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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