STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
furFerric ion uptake regulator; Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. (139 aa)    
Predicted Functional Partners:
ahpC
Similar to Streptomyces coelicolor alkyl hydroperoxide reductase AhpC SWALL:Q9RN72 (EMBL:AF186371) (184 aa) fasta scores: E(): 9.6e-31, 51.09% id in 182 aa, and to Ralstonia solanacearum putative alkyl hydroperoxide reductase AhpC2 or rsc1646 or rs04022 SWALL:Q8XYW0 (EMBL:AL646065) (230 aa) fasta scores: E(): 2.4e-63, 85.16% id in 182 aa.
  
  
 0.757
omlA
Outer membrane lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
  
 0.749
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.682
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
  
  
 0.638
BP0825
Similar to Vibrio cholerae hypothetical protein Vc2666 TR:Q9KNR5 (EMBL:AE004332) (205 aa) fasta scores: E(): 2.1e-30, 43.781% id in 201 aa, and to Bacillus halodurans Bh3429 protein Bh3429 TR:Q9K7D5 (EMBL:AP001518) (215 aa) fasta scores: E(): 3.8e-14, 31.818% id in 198 aa.
  
    0.610
trxA
Thioredoxin 1; Similar to Escherichia coli thioredoxin 1 TrxA or TsnC or FipA or B3781 SW:THIO_ECOLI (P00274) (108 aa) fasta scores: E(): 6.4e-28, 66.35% id in 107 aa, and to Pseudomonas aeruginosa thioredoxin TrxA or Trx or Pa5240 SW:THIO_PSEAE (Q9X2T1) (108 aa) fasta scores: E(): 7.2e-32, 75.92% id in 108 aa. Also similar to BP1713, 39.000% identity in 100 aa overlap.
  
 
 0.569
BP0965
Similar to Mus musculus antioxidant protein 2 Aop2 or Ltw4 or Prdx5 SW:AOP2_MOUSE (O08709) (223 aa) fasta scores: E(): 1.3e-42, 55.605% id in 223 aa, and to Pseudomonas aeruginosa probable antioxidant protein Pa3450 TR:Q9HYF6 (EMBL:AE004765) (212 aa) fasta scores: E(): 6.9e-68, 79.048% id in 210 aa.
  
  
 0.539
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 8.3e-106, 44.45% id in 1597 aa, and to Deinococcus radiodurans glutamate synthase, large subunit DR0183 TR:Q9RXX2 (EMBL:AE001880) (1615 aa) fasta scores: E(): 0, 70.42% id in 1579 aa.
     
 0.508
BP3082
Similar to Rhizobium loti ABC transporter, ATP-binding protein MLL8315 TR:Q983I5 (EMBL:AP003013) (272 aa) fasta scores: E(): 3.5e-36, 51.73% id in 230 aa, and to Neisseria meningitidis ABC transporter, ATP-binding protein NMB0588 TR:Q9K0K6 (EMBL:AE002415) (251 aa) fasta scores: E(): 2.5e-29, 47.11% id in 225 aa.
  
  
 0.504
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.496
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.