STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (88 aa)    
Predicted Functional Partners:
xseA
Exodeoxyribonuclease large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
 
 0.999
BP2799
Similar to Bradyrhizobium japonicum probable geranyltranstransferase SW:ISPA_BRAJA (Q45220) (332 aa) fasta scores: E(): 2.2e-42, 49.65% id in 288 aa; Belongs to the FPP/GGPP synthase family.
  
  
 0.927
recJ
Similar to Escherichia coli single-stranded-DNA-specific exonuclease RecJ or B2892 SW:RECJ_ECOLI (P21893) (577 aa) fasta scores: E(): 2.1e-86, 46.6% id in 575 aa, and to Neisseria meningitidis putative single-stranded-DNA-specific exonuclease RecJ or Nma1052 TR:Q9JV09 (EMBL:AL162755) (566 aa) fasta scores: E(): 3.2e-110, 54.32% id in 567 aa.
  
  
 0.818
dxs
1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.804
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
  
 0.732
HemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
   
    0.603
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
       0.602
BP2801
Similar in the C-terminus to many putative transcriptional regulators e.g. Rhizobium meliloti putative transcriptional regulator IclR family protein Smb20586 TR:CAC49898 (EMBL:AL603647) (251 aa) fasta scores: E(): 6.9e-13, 30.08% id in 246 aa. Similar over the entire range to Pseudomonas putida pca regulon regulatory protein PcaR SW:PCAR_PSEPU (Q52154) (291 aa) fasta scores: E(): 3.1e-12, 27.64% id in 293 aa.
  
    0.556
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.531
rpsF
30s ribosomal protein s6; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.526
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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