STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgi-2Similar to Homo sapiens glucose-6-phosphate isomerase Gpi TR:Q9BSK5 (EMBL:M61214) (558 aa) fasta scores: E(): 1.7e-68, 42.26% id in 504 aa, and to Escherichia coli glucose-6-phosphate isomerase Pgi or B4025 or Z5623 or Ecs5008 TR:AAG59224 (EMBL:X15196) (549 aa) fasta scores: E(): 3.5e-61, 37.69% id in 520 aa. Also similar to BP1971, 40.891% identity (43.238% ungapped) in 516 aa overlap. (521 aa)    
Predicted Functional Partners:
pgm-2
Phosphoglucomutase; Identical to the Bordetella bronchiseptica phosphoglucomutase Pgm TR:Q9S3V9 (EMBL:AF171632) (392 aa) fasta scores: E(): 1.1e-149, 99.23% id in 392 aa, and similar to Pseudomonas aeruginosa phosphomannomutase AlgC or PA5322 SW:ALGC_PSEAE (P26276) (462 aa) fasta scores: E(): 3.9e-93, 53.26% id in 460 aa, and to Neisseria meningitidis phosphoglucomutase Pgm or NMB0790 SW:PGMU_NEIMB (P40391) (460 aa) fasta scores: E(): 1.2e-91, 54.54% id in 440 aa, and to Neisseria gonorrhoeae phosphoglucomutase PGM SW:PGMU_NEIGO (P40390) (460 aa) fasta scores: E(): 1.3e-90, 53.52% id i [...]
  
 
 0.979
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.968
tktA
Transketolase 1; Similar to Escherichia coli transketolase 1 TktA or Tkt or B2935 SW:TKT1_ECOLI (P27302) (663 aa) fasta scores: E(): 5.7e-137, 63.433% id in 670 aa, and to Pasteurella multocida transketolase 1 TktA or Pm1242 SW:TKT1_PASMU (P57927) (668 aa) fasta scores: E(): 3e-158, 61.504% id in 678 aa; Belongs to the transketolase family.
  
 0.967
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
 
 
 0.965
pykA
Pyruvate kinase; Similar to Escherichia coli pyruvate kinase II PykA or b1854 SW:KPY2_ECOLI (P21599) (479 aa) fasta scores: E(): 2.1e-96, 59.32% id in 477 aa.
 
 
 0.961
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.950
gap
Similar to Pseudomonas aeruginosa glyceraldehyde 3-phosphate dehydrogenase Gap or HexC or pa3195 SWALL:G3P_PSEAE (SWALL:P27726) (334 aa) fasta scores: E(): 9.1e-84, 66.07% id in 336 aa, and to Alcaligenes eutrophus glyceraldehyde 3-phosphate dehydrogenase, plasmid cbbgP SWALL:G3PP_ALCEU (SWALL:P50322) (336 aa) fasta scores: E(): 1.1e-107, 84.52% id in 336 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.946
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.941
gpmA
Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
  
 
 0.923
fbp
Fructose-1,6-bisphosphatase; Similar to Escherichia coli fructose-1,6-bisphosphatase Fbp or Fdp or B4232 SW:F16P_ECOLI (P09200) (332 aa) fasta scores: E(): 3.1e-49, 47.273% id in 330 aa, and to Pseudomonas aeruginosa fructose-1,6-bisphosphatase Fbp or Pa5110 TR:Q9HU73 (EMBL:AE004923) (336 aa) fasta scores: E(): 2.6e-97, 73.591% id in 337 aa.
   
 
 0.919
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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