STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BP3543Putative D-isomer specific 2-hydroxyacid dehydrogenase; Similar to Hyphomicrobium methylovorum glycerate dehydrogenase SW:DHGY_HYPME (P36234) (321 aa) fasta scores: E(): 9.8e-27, 32.29% id in 322 aa, and to Agrobacterium tumefaciens hypothetical protein AGR_L_379p TR:AAK88759 (EMBL:AE008217) (311 aa) fasta scores: E(): 1.6e-49, 47.26% id in 311 aa; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)    
Predicted Functional Partners:
BP0250
Putative exported protein; Similar to Rhizobium meliloti conserved hypothetical protein Sma1927 TR:AAK65716 (EMBL:AE007292) (330 aa) fasta scores: E(): 1.1e-49, 44.207% id in 328 aa, and to Comamonas testosteroni OrfJ protein TR:Q9RHM9 (EMBL:AB029044) (326 aa) fasta scores: E(): 1.3e-40, 39.752% id in 322 aa.
  
  
 0.663
BP1532
Putative amino acid-binding periplasmic protein; Similar to Escherichia coli cystine-binding periplasmic protein precursor FliY or B1920 SW:FLIY_ECOLI (P39174) (266 aa) fasta scores: E(): 3.8e-16, 30.38% id in 260 aa, and to Salmonella typhimurium FliY TR:Q9ZNM2 (EMBL:AB010947) (266 aa) fasta scores: E(): 1.9e-16, 31.03% id in 261 aa.
  
  
 0.663
BP3575
Putative exported protein; Similar to Pseudomonas aeruginosa leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein precursor BraC SW:BRAC_PSEAE (P21175) (373 aa) fasta scores: E(): 0.0012, 20.4% id in 343 aa, and to Agrobacterium tumefaciens hypothetical protein AGR_L_1462p TR:AAK89309 (EMBL:AE008271) (402 aa) fasta scores: E(): 1e-77, 51.25% id in 400 aa.
      
 0.640
BP3542
Similar to Picea abies short-chain type dehydrogenase/reductase SW:SDR1_PICAB (Q08632) (271 aa) fasta scores: E(): 2.1e-15, 31.25% id in 240 aa, and to Pseudomonas aeruginosa probable short-chain dehydrogenase PA2918 TR:Q9HZS9 (EMBL:AE004718) (257 aa) fasta scores: E(): 1.8e-69, 82.57% id in 241 aa.
 
 
 0.589
BP3544
Putative lipoprotein; Similar to Rhizobium meliloti hypothetical protein SMA1927 TR:AAK65716 (EMBL:AE007292) (330 aa) fasta scores: E(): 9.7e-43, 39.62% id in 318 aa, and to Agrobacterium tumefaciens hypothetical protein AGR_L_312p TR:AAK88723 (EMBL:AE008213) (329 aa) fasta scores: E(): 1.6e-39, 38.8% id in 317 aa.
  
    0.530
nnrE
Hypothetical protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.
 
   0.489
maeB-3
Similar to Escherichia coli NADP-dependent malic enzyme MaeB SW:MAO2_ECOLI (P76558) (759 aa) fasta scores: E(): 1.6e-175, 60.07% id in 759 aa, and to Rhizobium meliloti NAD-dependent malic enzyme Dme SW:MAO1_RHIME (O30807) (770 aa) fasta scores: E(): 3.4e-169, 58.49% id in 759 aa.
  
 
 0.481
maeB
Similar to Escherichia coli NADP-dependent malic enzyme Maeb or B2463 SW:MAO2_ECOLI (P76558) (759 aa) fasta scores: E(): 1.3e-173, 59.81% id in 759 aa, and to Haemophilus influenzae NADP-dependent malic enzyme MaeB or hi1245 SW:MAO2_HAEIN (P43837) (756 aa) fasta scores: E(): 3.1e-168, 58.1% id in 759 aa. Almost identical to BP3456 (97.082% identity in 754 aa overlap), and highly similar to BP1120 (63.900% identity in 759 aa overlap).
  
 
 0.478
maeB-2
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or B2463 SW:MAO2_ECOLI (P76558) (759 aa) fasta scores: E(): 8.6e-184, 62.13% id in 758 aa, and to Pasteurella multocida Mdh Mdh_1 or pm0002 TR:Q9CPN5 (EMBL:AE006034) (758 aa) fasta scores: E(): 5.8e-179, 62.48% id in 757 aa.
  
 
 0.478
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.478
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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